yam61(2)_110.pdf 2.6 MB
cancer antigen 125
magnetic resonance imaging
maximum tumor diameter
Background: We investigated the distinguishing pathological features of bilateral ovarian tumors using magnetic resonance (MR) imaging.
Methods: Eighty-six patients with bilateral ovarian tumors on MR imaging were evaluated. The pathological diagnosis was investigated, and the results were subjected to statistical analysis using Mann-Whitney U test, Fisher’s exact test, Chi-squared test and receiver operating characteristic (ROC) curve to determine the features useful for the differentiation of distinct types of lesions.
Results: The diagnosis of bilateral ovarian tumors was confirmed in eighty-one patients and the majority of the lesions were further classified into serous carcinoma (n = 36), mature teratoma (n = 20) and metastasis (n = 12). We assessed the existence of factors useful for the MR imaging differentiation between metastasis and serous carcinoma or primary malignant ovarian tumors. Cancer antigen (CA) 125 serum level and maximum tumor diameter were significantly different between metastasis and serous carcinoma and similarly, between metastasis and primary malignant ovarian tumors. MR imaging morphology, ascites and peritoneal implants did not show any significant difference between the different types of lesions.
Conclusion: Within our patient cohort, most bilateral ovarian tumor lesions were determined to be serous carcinoma, mature teratoma or metastasis. CA 125 serum level and maximum tumor diameter are useful markers for the differentiation between metastasis and serous carcinoma or primary malignant ovarian tumors.
Tottori University Faculty of Medicine
Yonago Acta Medica
|Current Journal Title||
Yonago Acta Medica
Yonago Acta Medica. 2018, 61(2), 110-116
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital