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Authors
Matsuura, Yuka Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Oguri, Masayoshi Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine Tottori University Researchers
Saito, Yoshiaki Division of Child Neurology, Department of Brain and Neurological Sciences, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Aoe, Yasutaka Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Ogawa, Ayame Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Akiyama, Shota Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Yasuda, Nanako Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Sato, Kengo Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine Tottori University Researchers
Maegaki, Yoshihiro Division of Child Neurology, Department of Brain and Neurological Sciences, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Hirooka, Yasuaki Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Keywords
auditory brain stem response
amplitude
fastigial nucleus
cerebellar vermis
Abstract
【Background】 This study aims to elucidate the effect of isolated cerebellar lesions sparing the brainstem on the auditory brainstem responses in children.
【Methods】 We enrolled 10 children (aged 1–16 years) with cerebellar lesions on neuroimaging but lacking clinical brainstem involvement signs and with normal brainstem volumes on magnetic resonance imaging.
【Results】 The interpeak latency of waves I and V was normal in 9 patients and was marginally prolonged in 1 patient. While amplitudes of waves I and III were normal, we noted a decreased amplitude of wave V and/or an increased I/V amplitude ratio in 6 patients; these
included 5 of 8 patients with cerebellar hypoplasia/atrophy and 1 patient with acute cerebellar ataxia.
【Conclusion】 Our results support the hypothesis of an inhibitory input from the cerebellar fastigial nucleus on the inferior colliculus, which might be disinhibited because of Purkinje cells dysfunction due to cerebellar cortex lesions, especially within the cerebellar vermis.
Publisher
Tottori University Faculty of Medicine
Content Type
Journal Article
ISSN・ISBN
13468049
NCID
AA00892882
Journal Title
Yonago Acta Medica
Current Journal Title
Yonago Acta Medica
Volume
61
Issue
4
Start Page
220
End Page
227
Published Date
2018
Text Version
Publisher
Rights
注があるものを除き、この著作物は日本国著作権法により保護されています。
Citation
Yonago Acta Medica. 2018, 61(4), 220-227
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English