File
Authors
Keywords
gastric carcinoma
peritoneal metastasis
prognosis
recurrence
NDC
Natural science
Abstract
[Background] Gastric cancer patients with peritoneal metastasis have an extremely poor prognosis. The aim of the current study was to clarify the predictive factors of a better outcome in gastric cancer patients with peritoneal metastasis.
[Methods] We analyzed the records of 2262 gastric adenocarcinoma patients who underwent gastrectomies at our institution between January 1980 and December 2010.
[Results] The 5-year survival rates for advanced gastric cancer patients with P1 (n = 43), P2 (n = 56), and P3 (n = 36) metastasis were 16.3%, 0%, and 0%, respectively. The prognosis of P1 gastric cancer patients was significantly better than that of either P2 (P = 0.0003) or P3 patients (P < 0.0001). A multivariate analysis identified gross appearance and curability as independent prognostic indicators in P1 gastric cancer patients. In fact, the prognosis was good for patients in whom an R0/1 resection had been performed and with tumors having a gross appearance of other than type 4, with a 40% 5-year survival rate and a 29-month median survival time.
[Conclusion] Our data indicated a good prognosis for P1 patients in whom an R0/1 resection could be performed and with tumors having a gross appearance of other than type 4. Therefore, radical surgery and adequate adjuvant chemotherapy should be performed in these patients.
Publisher
Tottori University Faculty of Medicine
Content Type
Journal Article
Link
http://www.lib.tottori-u.ac.jp/yam/yam/yam60-3/yam-60-174.pdf
ISSN・ISBN
1346-8049
NCID
AA00892882
Journal Title
Yonago Acta Medica
Current Journal Title
Yonago Acta Medica
Volume
60
Issue
3
Start Page
174
End Page
178
Published Date
2017-09-15
Text Version
Publisher
Citation
Yonago Acta Medica. 2017, 60(3), 174-178
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English