File
Authors
Keywords
CA19-9
cancer-associated antigen
idiopathic interstitial pneumonia
SLX
Abstract
We report a case of idiopathic interstitial pneumonia (IIP) with elevated serum levels of carbohydrate antigen 19-9 (CA19-9) and sialyl Lewisx-i (SLX). A 67-year-old Japanese woman was admitted to our hospital with a fever, dry cough and dyspnea on exertion. She had previously been admitted and had then been diagnosed as IIP. The serum level of SLX, measured by radioimmunoassay (RIA), was markedly elevated (120 U/mL; cut-off, < 38 U/mL). The serum level of CA19-9, measured by RIA, was at a slightly high level (46 U/mL; cut-off, < 40 U/mL). The values of CA19-9 and SLX were changed during her clinical course. These cancer-associated antigens were immunohistochemically expressed on the hyperplastic bronchiolar epithelium, on the surface epithelium cells of microscopic honeycombing and on exudates in air space. Repeated damage to the lungs may have forced these antigens of the markers into the blood circulation, which may have resulted in the elevated serum levels of CA19-9 and SLX observed in this patient.
Publisher
Tottori University Faculty of Medicine
Content Type
Journal Article
ISSN・ISBN
1346-8049
NCID
AA00892882
Journal Title
Yonago Acta medica
Current Journal Title
Yonago Acta medica
Volume
40
Issue
3
Start Page
147
End Page
151
Published Date
1997-11
Text Version
Publisher
Rights
Yonago Acta medica 編集委員会
Citation
Yonago Acta medica. 1997, 40(3), 147-151
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English