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Authors
Kuroda, Hirohiko Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine KAKEN Search Researchers
Saito, Hiroaki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Kono, Yusuke Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
Murakami, Yuki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers
Shishido, Yuji Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers
Matsunaga, Tomoyuki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers
Fukumoto, Yoji Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Osaki, Tomohiro Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine KAKEN Search Researchers
Ashida, Keigo Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Nosaka, Kanae Division of Organ Pathology, Department of Pathology, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers
Umekita, Yoshihisa Division of Organ Pathology, Department of Pathology, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Fujiwara, Yoshiyuki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Tottori University Researchers KAKEN Search Researchers
Keywords
carcinosarcoma
gastric cancer
stomach
Abstract
Carcinosarcoma is a malignant tumor composed of both epithelial and mesenchymal malignant tumor components. A 78-year-old man was transferred to our hospital because of hematemesis and tarry stool. An emergency gastrointestinal endoscopic examination revealed active bleeding from an ulcerative lesion on the posterior wall of the gastric body; endoscopic hemostasis was successfully performed. A gastrointestinal endoscopy performed two months later showed a polypoid lesion at the same place where the ulcer had been. The biopsy specimen was histologically diagnosed as well to moderately differentiated tubular adenocarcinoma. The patient underwent a laparoscopic distal gastrectomy with D2 lymph node dissection under a diagnosis of gastric adenocarcinoma. A 28 × 15 mm polypoid tumor was resected from the gastric body, and was found on microscopic examination to consist of both carcinoma and sarcoma components, showing atypical spindle cells, which were positive for α-smooth muscular actin, calponin, and h-caldesmon, but negative for CD34, CD117 (c-kit), desmin, and dog 1. These findings led to a diagnosis of gastric carcinosarcoma. The tumor was confined to the mucous membrane. Lymph node metastasis was found in one node and contained only the carcinoma component. The postoperative course was uneventful. The patient lived without recurrence for 2 years. Carcinosarcoma of the stomach is a rare tumor with high malignant potential and poor prognosis. Careful follow up is required for early detection of any recurrence.
Publisher
Tottori University Faculty of Medicine
Content Type
Journal Article
ISSN・ISBN
1346-8049
NCID
AA00892882
Journal Title
Yonago Acta Medica
Current Journal Title
Yonago Acta Medica
Volume
60
Issue
4
Start Page
246
End Page
250
Published Date
2018-02-05
Text Version
Publisher
Citation
Yonago Acta Medica. 2017, 60(4), 246-250
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English