File
Authors
Keywords
Fanconi syndrome
immunoelectron microscopy
multiple myeloma
Abstract
Multiple myeloma is uncommonly complicated with Fanconi syndrome, due to the deposition of light chains in renal tubular epithelial cells. A 76-year-old man with λ-Bence Jones type multiple myeloma had adult Fanconi syndrome. Electron microscopy showed that rhomboid, high-density substances of various sizes, were accumulated in the proximal tubular epithelial cells on renal biopsy. Immunoelectron microscopy demon-strated that these crystals were λ-light chains. The deposition of κ-light chain in patients with myeloma-associated Fanconi syndrome has been known. This is the 1st report showing the deposition of λ-light chain in renal proximal tubular epithelial cells.
Publisher
Tottori University Faculty of Medicine
Content Type
Journal Article
ISSN・ISBN
1346-8049
NCID
AA00892882
Journal Title
Yonago Acta medica
Current Journal Title
Yonago Acta medica
Volume
47
Issue
4
Start Page
91
End Page
96
Published Date
2004-12
Text Version
Publisher
Rights
Yonago Acta medica 編集委員会
Citation
Yonago Acta medica. 2004, 47(4), 91-96
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English