File
Authors
Keywords
follicular lymphoma
malignant lymphoma
mediastinal tumor
Abstract
We report a 58-year-old man who suffered from shortness of breath on exertion with wheezing. A chest enhanced computed tomography (CT) scan showed an irregular tumor in the middle mediastinum involving the right main pulmonary artery, vena cava superior and right main bronchus. Transbronchial lung biopsy and endobronchial ultrasoundguided transbronchial needle aspiration yielded no evidence for a pathological diagnosis of malignancy. We employed mediastinoscopy, which led to a diagnosis of lymphoid reactive change. 18F-fluorodeoxyglucose-positron emission omography (FDG-PET) scan revealed a high FDG uptake in the tumor lesion. Because the CT scan and FDG-PET findings led to a marked suspicion of malignancy, we decided to attempt biopsy by a video-assisted thoracoscopic surgery (VATS) approach. Flow cytometry showed a monoclonal pattern, and the final diagnosis was mediastinal follicular lymphoma both pathologically and immunohistologically. The patient achieved a complete remission by following chemotherapy. Lowgrade malignancy type of lymphoma such as follicular lymphoma that generally contains small-cell components often presents a diagnostic challenge and the VATS approach was effective for the diagnosis of such type of mediastinal lymphoma.
Publisher
Tottori University Faculty of Medicine
Content Type
Journal Article
Link
ISSN・ISBN
1346-8049
NCID
AA00892882
Journal Title
Yonago Acta medica
Current Journal Title
Yonago Acta medica
Volume
54
Issue
4
Start Page
83
End Page
86
Published Date
2011-12
Text Version
Publisher
Citation
Yonago Acta medica. 2011, 54(4), 83-86
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English