フルテキストファイル
著者
Saito Hiroaki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Kono Yusuke Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
Murakami Yuki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧
Shishido Yuji Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧
Kuroda Hirohiko Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine KAKEN研究者をさがす
Matsunaga Tomoyuki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧
Fukumoto Yoji Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Osaki Tomohiro Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine KAKEN研究者をさがす
Ashida Keigo Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Fujiwara Yoshiyuki Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
キーワード
age
albumin
gastric cancer
malnutrition
prognosis
NDC分類
4類 自然科学
抄録
【Background】 The incidence of gastric cancer (GC) among older adults is increasing. Therefore, determining postoperative age-associated prognostic factors is clinically important. This study retrospectively investigated the prognostic significance of serum albumin level in older GC patients.
【Methods】 We enrolled 135 patients aged ≥ 75 years, who underwent gastrectomies with histopathological diagnoses of gastric adenocarcinoma.
【Results】 Preoperative albumin (pre-Alb) levels in patients with advanced GC and stage III/IV GC were significantly lower than those in patients with early GC (P = 0.0032) and stage I/II GC (P = 0.006), respectively. Postoperative albumin (post-Alb) levels (measured 1 month after surgery) in male patients and in patients with advanced GC were significantly lower than those in female patients (P = 0.024) and those with early GC (P = 0.044), respectively. Post-Alb levels of patients who died of other diseases were significantly lower than those who were still living (P = 0.0004). Prognosis of patients with high post-Alb levels (≥ 4g/dL) was significantly better than that of patients with low post-Alb levels (< 4g/dL; P = 0.045); and in multivariate analysis, post-Alb level was an independent prognostic indicator.
【Conclusion】 Post-Alb level is a useful predictive factor for the prognosis of older GC patients. Postoperative nutritional support might help improve the prognosis of older GC patients.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN・ISBN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta Medica
最新掲載誌名
Yonago Acta Medica
61
1
開始ページ
72
終了ページ
78
発行日
2018-03-28
著者版フラグ
出版社版
掲載情報
Yonago Acta Medica. 2018, 61(1), 72-78
部局名
医学部・医学系研究科・医学部附属病院
言語
英語