フルテキストファイル
著者
Uchida Naotaka Division of Organ Regeneration Surgery, Department of Surgery, Tottori University Faculty of Medicine
Ishiguro Kiyosuke Division of Organ Regeneration Surgery, Department of Surgery, Tottori University Faculty of Medicine KAKEN
Nakamura Keiko Division of Organ Regeneration Surgery, Department of Surgery, Tottori University Faculty of Medicine
Suda Takako Division of Organ Regeneration Surgery, Department of Surgery, Tottori University Faculty of Medicine
Nishimura Motonobu Division of Organ Regeneration Surgery, Department of Surgery, Tottori University Faculty of Medicine 研究者総覧 KAKEN
キーワード
breast cancer
sentinel lymph node biopsy
抄録
To demonstrate the validity of sentinel lymph node biopsy (SLNB) using the indocyanine green dye method (dye only method), we compared the survival of breast cancer patients negative to SLNB without axillary lymph node dissection (ALND) (SLNB group) to that of lymph node-negative patients undergoing ALND (ALND group). We studied a total of 174 patients with T1-2N0 invasive breast cancer diagnosed at our university hospital clinical department between 2000 and 2008, with follow-up till 31 December 2009, retrospectively. The SLNB group consisted of 108 SLNB-negative women without additional ALND (median follow-up, 25 months), diagnosed between May 2005 and 2008. The ALND group consisted of 66 axillary lymph node-negative women (median follow-up, 75 months) treated with ALND between 2000 and April 2005. SLNB was performed during operation by periareolar injection using indocyanine green. All sentinel lymph nodes were examined using the largest section along the major axis, and permanent sections were stained with hematoxylin and eosin. In the SLNB group, no patients developed axillary recurrence during the 25-month median follow-up. The 4.5-year distant disease free survival and overall survival rates were 90.9% and 91.9%, respectively. The survival rate in the SLNB group was equivalent to that in the ALND group. This suggests that SLNB with the dye only method can safely replace ALND as the procedure of choice for axillary staging in breast cancer patients with a clinically negative axilla.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
外部リンク
ISSN・ISBN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
53
2
開始ページ
47
終了ページ
52
発行日
2010-06
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 2010, 53(2), 47-52
部局名
医学部・医学系研究科・医学部附属病院
言語
英語