フルテキストファイル
著者
Kimura, Yusuke Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧
Honda, Masashi Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Morizane, Shuichi Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Hikita, Katsuya Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Isoyama, Tadahiro Torrori Prefectual Central Hospital
Ono, Koji Japanese Red Cross Tottori Hospital
Koumi, Tsutomu Japanese Red Cross Tottori Hospital
Takahashi, Chihiro Yonago Medical Center
Takenaka, Atsushi Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
キーワード
bacilli calmette-guerin therapy
bladder cancer
second transurethral resection
抄録
Background: To evaluate the efficacy of Bacilli Calmette-Guerin (BCG) induction instillation therapy after second transurethral resection (TUR) in stage Ta T1 high-grade bladder cancer.
Methods: We performed a retrospective analysis of 49 consecutive new onset Ta T1 high-grade bladder cancer patients treated with second TUR at our affiliated institutions. Residual cancer rate, intravesical recurrence-free survival (RFS), and risk factors related to RFS were evaluated by univariate and multivariate Cox proportional hazard model analyses.
Results: Thirty-one patients received BCG therapy after the second TUR (BCG group), and 18 patients were treated with second TUR alone (no BCG group). There were statistically significant differences in the RFS rates between the two groups, (P = 0.037). BCG therapy was the only factor predictive of intravesical recurrence after second TUR in both univariate and multivariate analyses. After the second TUR, BCG therapy significantly decreased intravesical recurrence in the patients with residual tumors (P = 0.014). However, there was no significant difference in intravesical recurrence in the patients with no residual tumors between the two groups (P = 0.359).
Conclusion: BCG therapy after second TUR significantly decreased intravesical recurrence of residual tumors found at the second TUR.
出版者
Tottori University Medical Press
資料タイプ
学術雑誌論文
外部リンク
ISSN・ISBN
05135710
書誌ID
AA00892882
掲載誌名
Yonago Acta Medica
最新掲載誌名
Yonago Acta Medica
62
2
開始ページ
191
終了ページ
197
発行日
2019-06-20
出版者DOI
著者版フラグ
出版社版
著作権表記
注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.
掲載情報
Yusuke Kimura, Masashi Honda, Shuichi Morizane, Katsuya Hikita, Tadahiro Isoyama, Koji Ono, Tsutomu Koumi, Chihiro Takahashi, Atsushi Takenaka, Effect of Intravesical Bacilli Calmette-Guerin Therapy After Second Transurethral Resection in Stage Ta T1 High-Grade Bladder Cancer, Yonago Acta Medica, 2019, Volume 62, Issue 2, Pages 191-197
部局名
医学部・医学系研究科・医学部附属病院
言語
英語