フルテキストファイル
著者
Matsuura Yuka Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Oguri Masayoshi Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine 鳥取大学研究者総覧
Saito Yoshiaki Division of Child Neurology, Department of Brain and Neurological Sciences, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Aoe Yasutaka Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Ogawa Ayame Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Akiyama Shota Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Yasuda Nanako Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Sato Kengo Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine 鳥取大学研究者総覧
Maegaki Yoshihiro Division of Child Neurology, Department of Brain and Neurological Sciences, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
Hirooka Yasuaki Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine 鳥取大学研究者総覧 KAKEN研究者をさがす
キーワード
auditory brain stem response
amplitude
fastigial nucleus
cerebellar vermis
抄録
【Background】 This study aims to elucidate the effect of isolated cerebellar lesions sparing the brainstem on the auditory brainstem responses in children.
【Methods】 We enrolled 10 children (aged 1–16 years) with cerebellar lesions on neuroimaging but lacking clinical brainstem involvement signs and with normal brainstem volumes on magnetic resonance imaging.
【Results】 The interpeak latency of waves I and V was normal in 9 patients and was marginally prolonged in 1 patient. While amplitudes of waves I and III were normal, we noted a decreased amplitude of wave V and/or an increased I/V amplitude ratio in 6 patients; these
included 5 of 8 patients with cerebellar hypoplasia/atrophy and 1 patient with acute cerebellar ataxia.
【Conclusion】 Our results support the hypothesis of an inhibitory input from the cerebellar fastigial nucleus on the inferior colliculus, which might be disinhibited because of Purkinje cells dysfunction due to cerebellar cortex lesions, especially within the cerebellar vermis.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN・ISBN
13468049
書誌ID
AA00892882
掲載誌名
Yonago Acta Medica
最新掲載誌名
Yonago Acta Medica
61
4
開始ページ
220
終了ページ
227
発行日
2018
著者版フラグ
出版社版
著作権表記
注があるものを除き、この著作物は日本国著作権法により保護されています。
掲載情報
Yonago Acta Medica. 2018, 61(4), 220-227
部局名
医学部・医学系研究科・医学部附属病院
言語
英語