フルテキストファイル
著者
Kaneko Tetsuya First Department of Surgery, Faculty of Medicine, Tottori University KAKEN
Cai Jianhui First Department of Surgery, Faculty of Medicine, Tottori University
Ishikura Takanori First Department of Surgery, Faculty of Medicine, Tottori University
Kobayashi Makoto First Department of Surgery, Faculty of Medicine, Tottori University
Naka Takuji First Department of Surgery, Faculty of Medicine, Tottori University
Kaibara Nobuaki First Department of Surgery, Faculty of Medicine, Tottori University KAKEN
キーワード
haloperidol
postoperative delirium
抄録
Postoperative delirium has in recent years been a common complication which can interfere with the recovery of patients after surgery. Unfortunately there is still no medical procedure available which can completely prevent the occurrence of postoperative delirium. Haloperidol is a psychopharmacological agent that has been used to treat the delirium and agitation, especially in geriatric patients. To assess the effectiveness and safety of the use of haloperidiol for the reduction of postoperative delirium, we performed a randomized, comparative clinical study in which 78 patients who underwent gastrointestinal surgery received either 5 mg of haloperidol intravenously postoperatively at 21:00 for 5 consecutive days, or normal saline with the same schedule. Postsurgical evaluation revealed the incidence of postoperative delirium to be only 10.5% (4 of 38 patients) in the group receiving haloperidol treatment, compared to 32.5% (13 of 40 patients) in the saline treatment group. No significant neuroleptic side effects were seen in any of the patients. These results suggest that daily postoperative administration of haloperidol can reduce the occurrence of postoperative delirium safely.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN・ISBN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
42
3
開始ページ
179
終了ページ
184
発行日
1999-11
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 1999, 42(3), 179-184
部局名
医学部・医学系研究科・医学部附属病院
言語
英語