ID 12449
File
Authors
Oshima, Yoshiaki Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine / Department of Anesthesiology, Yonago Medical Center
Okazaki, Naoto Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
Funaki, Kazumi Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Researchers DB KAKEN
Takahashi, Shunsaku Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine / Department of Anesthesiology, Tottori Prefectural Central Hospital
Harada, Tomomi Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine / Department of Anesthesiology, Ehime Prefectural Central Hospital KAKEN
Otsuki, Akihiro Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Researchers DB KAKEN
Inagaki, Yoshimi Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine Researchers DB KAKEN
Keywords
hypoxia
oxygen consumption
prone position
respiratory distress syndrome
Abstract
Ventilation in the prone position improves the prognosis of patients with severe acute respiratory distress syndrome (ARDS). Contraindications to ventilation in this position include unstable systemic circulation. Only a few reports exist on the effects of prone ventilation in respiratory failure on systemic circulation. This animal study compared systemic hemodynamic changes between supine and prone positions in anesthetized rabbits under acute systemic hypoxia (breathing 15% O2). Cardiac output and the systemic O2 extraction ratio increased under the hypoxia, but only in the supine group. Besides, the rate pressure product was higher in the prone group than in the supine group. This study showed that prone ventilation increases myocardial O2 consumption and suppresses compensatory mechanisms to maintain aerobic metabolism during systemic hypoxia. First of all, it will be necessary to examine the effect of prone ventilation on the O2 supply-demand balance in the ARDS model.
Publisher
Tottori University Medical Press
Content Type
Journal Article
Link
ISSN
05135710
EISSN
13468049
NCID
AA00892882
Journal Title
Yonago Acta Medica
Current Journal Title
Yonago Acta Medica
Volume
64
Issue
2
Start Page
229
End Page
233
Published Date
2021-05-20
Publisher-DOI
Text Version
Publisher
Rights
(C) 2021 Tottori University Medical Press
Citation
Oshima Yoshiaki, Okazaki Naoto, Funaki Kazumi, et al. Prone Position Impairs Oxygen Supply-Demand Balance During Systemic Hypoxia in Rabbits. Yonago Acta Medica. 2021, 64(2), 229-233. doi:10.33160/yam.2021.05.012
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English