ハイドロキシアパタイト填入長期間経過後感染し除去した2例

Hydroxyapatite （HA） has been used out as bone filling material in bone defects from various disease. Although there are some reports short-term postoperative infection of HA, there are few reports long-term postoperative infection of HA. We reported 2 cases of dental infection that HA filling region of mandible bone and removal of infected HA after long periods. One case who was underwent excision of cyst and apicoectomy and filled HA to bone defect one case resulting from excision of cyst of mandible twenty years ago. The other case who was underwent segmental resection of the mandible and reconstructed by reconstruction plate, HA block and pectoral major musculo-cutaneous flap because of cancer of floor of mouth twenty years ago. Both of two cases referred to our hospital because of swelling and pain in the same region and removed infected HA. There are still many cases filled HA to bone defect. In case we encounter the cases filled HA to bone defect, we need to pay attention to infection of HA and must call attention to the risk of HA to patients.