魚うろこ由来コラーゲン過剰摂取の安全性

The safety of excessive intake of collagen polypeptides （‘EMFCTR-01’; the commercial name ‘Tenshi no RaRa’） extracted from fish scales has been examined by the single group study of 10 healthy volunteers consisting of 4 females and 6 males between 20 and 45 years old. The participants consumed the collagen ‘EMFCTR-01’ of the amount five times as much as usual consumption for 4 consecutive weeks. There were no abnormal changes in physical examination, electrocardiogram, hematological examination, blood biochemical analysis and urinalysis. Although the frequency of the daily defecation was increased during the trial of collagen ‘EMFCTR-01’ consumption, it was considered that the collagen might improve the intestinal environment because there were no changes in the stool output as well as fecal properties. Thus, the safety of collagen‘ EMFCTR-01’ was confirmed.