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Authors
Nishii-Ito, Shizuka Department of Hematology, Tottori University Hospital / Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Izumi, Hiroki Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Touge, Hirokazu Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Takeda, Kenichi Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Hosoda, Yuzuru Department of Hematology, Tottori University Hospital / Division of Clinical Laboratory Medicine, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University Researchers DB
Yamasaki, Akira Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University Researchers DB KAKEN
Kuwamoto, Satoshi Division of Molecular Pathology, Department of Pathology, Faculty of Medicine, Tottori University Researchers DB KAKEN
Shimizu, Eiji Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University KAKEN
Motokura, Toru Department of Hematology, Tottori University Hospital / Division of Clinical Laboratory Medicine, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University Researchers DB KAKEN
Keywords
intravascular large B-cell lymphoma
rituximab
ground-glass opacities
Abstract
A 73-year-old man with a history of lethargy, fever and dyspnea was admitted to Tottori University Hospital. A computed tomography (CT) scan revealed splenomegaly and diffusely spreading ground‑glass opacities (GGOs) in both lungs. A video‑assisted thoracoscopic surgery (VATS)‑guided lung biopsy revealed intravascular proliferation of large atypical lymphoid cells in the arteries, veins and alveolar walls. The patient was diagnosed with intravascular large B‑cell lymphoma (IVLBCL); he received 6 cycles of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R‑CHOP) immunochemotherapy and has remained in complete remission for >1 year. Although IVLBCL is a rare disease, it should be considered in the differential diagnosis of pulmonary diffuse lesions that present with GGOs on CT scans.
Publisher
Spandidos Publications
Content Type
Journal Article
Link
ISSN
20499450
EISSN
20499469
Journal Title
MOLECULAR AND CLINICAL ONCOLOGY
Current Journal Title
MOLECULAR AND CLINICAL ONCOLOGY
Volume
5
Issue
6
Start Page
689
End Page
692
Published Date
2016-12
Publisher-DOI
Text Version
Publisher
Rights
© Nishii‑Ito et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Citation
Nishii-Ito Shizuka, Izumi Hiroki, Touge Hirokazu, et al. Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year. MOLECULAR AND CLINICAL ONCOLOGY. 2016. 5(6). 689-692. doi:10.3892/mco.2016.1063
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English
Web of Science Key ut
WOS:000453169800004