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Authors |
Nishii-Ito, Shizuka
Department of Hematology, Tottori University Hospital / Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Izumi, Hiroki
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Touge, Hirokazu
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Takeda, Kenichi
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Hosoda, Yuzuru
Department of Hematology, Tottori University Hospital / Division of Clinical Laboratory Medicine, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University
Researchers DB
Yamasaki, Akira
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
Researchers DB
KAKEN
Kuwamoto, Satoshi
Division of Molecular Pathology, Department of Pathology, Faculty of Medicine, Tottori University
Researchers DB
KAKEN
Shimizu, Eiji
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
KAKEN
Motokura, Toru
Department of Hematology, Tottori University Hospital / Division of Clinical Laboratory Medicine, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University
Researchers DB
KAKEN
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Keywords | intravascular large B-cell lymphoma
rituximab
ground-glass opacities
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Abstract | A 73-year-old man with a history of lethargy, fever and dyspnea was admitted to Tottori University Hospital. A computed tomography (CT) scan revealed splenomegaly and diffusely spreading ground‑glass opacities (GGOs) in both lungs. A video‑assisted thoracoscopic surgery (VATS)‑guided lung biopsy revealed intravascular proliferation of large atypical lymphoid cells in the arteries, veins and alveolar walls. The patient was diagnosed with intravascular large B‑cell lymphoma (IVLBCL); he received 6 cycles of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R‑CHOP) immunochemotherapy and has remained in complete remission for >1 year. Although IVLBCL is a rare disease, it should be considered in the differential diagnosis of pulmonary diffuse lesions that present with GGOs on CT scans.
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Publisher | Spandidos Publications
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Content Type |
Journal Article
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ISSN | 20499450
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EISSN | 20499469
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Journal Title | MOLECULAR AND CLINICAL ONCOLOGY
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Current Journal Title |
MOLECULAR AND CLINICAL ONCOLOGY
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Volume | 5
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Issue | 6
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Start Page | 689
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End Page | 692
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Published Date | 2016-12
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Publisher-DOI | |
Text Version |
Publisher
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Rights | © Nishii‑Ito et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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Citation | Nishii-Ito Shizuka, Izumi Hiroki, Touge Hirokazu, et al. Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year. MOLECULAR AND CLINICAL ONCOLOGY. 2016. 5(6). 689-692. doi:10.3892/mco.2016.1063
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Department |
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
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Language |
English
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Web of Science Key ut | WOS:000453169800004
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