| File | |
| Authors |
Nakamura, Yoko
Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University
Yamada, Saki
Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University
Nishikawa, Shoko
Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University
Matsuura, Kazunori
Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University
Researchers DB
KAKEN
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| Abstract | β-Annulus peptides from tomato bushy stunt virus conjugated with DNAs (dA20 and dT20) at the C-terminal were synthesized. The DNA-modified β-annulus peptides self-assembled into artificial viral capsids with sizes of 45-160 nm. ζ-Potential measurements revealed that the DNAs were coated on the surface of artificial viral capsids. Fluorescence assays indicated that the DNAs on the artificial viral capsids were partially hybridized with the complementary DNAs. Moreover, the DNA-modified artificial viral capsids formed aggregates by adding complementary polynucleotides.
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| Publisher | Wiley
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| Content Type |
Journal Article
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| Link | |
| ISSN | 10991387
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| NCID | AA11623882
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| Journal Title | Journal of peptide science
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| Current Journal Title |
Journal of peptide science
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| Volume | 23
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| Issue | 7-8
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| Start Page | 636
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| End Page | 643
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| Published Date | 2017-08-07
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| Publisher-DOI | |
| Text Version |
Author
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| Rights | Copyright © 2017 European Peptide Society and John Wiley & Sons, Ltd.
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| Citation | This is the peer reviewed version of the following article: Nakamura Y, Yamada S, Nishikawa S, Matsuura K, DNA-modified Artificial Viral Capsids self-assembled from DNA-conjugated β-Annulus Peptide. Journal of peptide science. 2017, 23, 636 , which has been published in final form at https://doi.org/10.1002/psc.2967. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
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| Department |
Faculty of Engineering/Graduate School of Engineering
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| Language |
English
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