File
Authors
Watanabe, Jun Department of Surgery, Tottori Prefectural Central Hospital
Endo, Kanenori Department of Surgery, Tottori Prefectural Central Hospital
Tanaka, Yasutaka Department of Surgery, Tottori Prefectural Central Hospital
Goto, Keisuke Department of Surgery, Tottori Prefectural Central Hospital
Urushibara, Shoichi Department of Surgery, Tottori Prefectural Central Hospital
Osaki, Tomohiro Department of Surgery, Tottori Prefectural Central Hospital KAKEN
Tatebe, Shigeru Department of Surgery, Tottori Prefectural Central Hospital
Nakamura, Seiichi Department of Surgery, Tottori Prefectural Central Hospital KAKEN
Hirooka, Yasuaki Department of Surgery, Tottori Prefectural Central Hospital Researchers DB KAKEN
Ikeguchi, Masahide Department of Surgery, Tottori Prefectural Central Hospital KAKEN
Keywords
abdomen
computed tomography
liver
vasodilator agents
Abstract
Background: Dynamic computed tomography (CT) angiography is useful for evaluating of hepatic vascularity. Although vasodilators increase hepatic blood flow, the utility of dynamic CT with vasodilators is unclear. Here we investigated the utility and safety of dynamic CT with vasodilators.

Methods: A prospective case-control radiographic evaluation using abdominal dynamic CT with and without vasodilator was performed at a single center between October 2015 and September 2016. We compared the CT values in Hounsfield units of the aorta; celiac artery; and common, right, and left hepatic arteries in the arterial phase and the main trunk; right and left branches of the portal vein; and right, middle, and left hepatic veins in the portal phase with and without vasodilators. The region of interest was set in each element of the liver vasculature. Four radiological technologists independently and visually compared the scores of the portal vein (P-score) and hepatic vein (V-score) on a 5-point scale with and without vasodilators.

Results: The CT values of arteries and veins using vasodilators were significantly higher than those without vasodilators. With and without vasodilators, the P-scores were 3.1 ± 1.2 and 4.0 ± 1.1 (P < 0.05) and the V-scores were 3.3 ± 1.4 and 4.3 ± 1.0 (P < 0.05). Only one patient with vasodilator use had transient hypotension and recovered immediately without medication.

Conclusion: Dynamic CT with vasodilators can provides better visualization of vascular structures.
Publisher
Tottori University Medical Press
Content Type
Journal Article
Link
ISSN
05135710
NCID
AA00892882
Journal Title
Yonago Acta Medica
Current Journal Title
Yonago Acta Medica
Volume
63
Issue
1
Start Page
47
End Page
54
Original Article
Published Date
2020-02-20
Publisher-DOI
Text Version
Publisher
Rights
注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.
Citation
Jun Watanabe, Kanenori Endo, Yasutaka Tanaka, Keisuke Goto, Shoichi Urushibara, Tomohiro Osaki, Shigeru Tatebe, Seiichi Nakamura, Yasuaki Hirooka, Masahide Ikeguchi, Investigation of the Utility and Safety of Dynamic Computed Tomography with Vasodilators, Yonago Acta Medica, 2020, Volume 63, Issue 1, Pages 47-54, Released February 20, 2020
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English