Chronic Fatigue Syndrome and IgA Nephropathy Occurring in the Same Patient

We report a patient with a rare association of chronic fatigue syndrome (CFS) and IgA nephropathy (IgAN). The patient was a 45-year-old woman who presented initially with biopsy proven IgAN and 2 years later developed CFS. Because of proteinuria and hematuria, she was referred to our clinic. A renal biopsy done at that time revealed IgAN. Then she was struck by the sudden onset of profound fatigue. According to criteria published by the Centers for Disease Control and Prevention in the United States, we diagnosed her illness as CFS.