File
Authors
Burioka, Naoto Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine Researchers DB KAKEN
Nakamoto, Sachiko Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine KAKEN
Amisaki, Takashi Department of Biological Regulation, School of Health Science, Tottori University Faculty of Medicine Researchers DB KAKEN
Horie, Takuya Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Shimizu, Eiji Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine KAKEN
Keywords
β(2)-agonist
chronic obstructive pulmonary disease
6-min walk test
procaterol
steps
Abstract
[Objective] The 6-min walk test (6MWT) is a simple test that is used to examine the exercise tolerance and outcomes in patients with chronic obstructive pulmonary disease (COPD). Although the 6MWT is useful for assessing exercise tolerance, it is difficult to evaluate time-dependent parameters such as the walking pattern. A modified 6MWT has been devised to assess the walking pattern by calculating the number of steps per second (NSPS). This study was performed to investigate walking pattern of COPD patients in the modified 6MWT before and after a single inhalation of the short-acting β2-agonist procaterol. [Methods] Nine male COPD patients participated in this study. The 6MWT was performed before and after the inhalation of procaterol hydrochloride. A digital video recording of the 6MWT was made. After the 6MWT, the number of steps walked by the subject in each 5-s period was counted manually with a hand counter while viewing the walking test on the video monitor. [Results] After the inhalation of procaterol, the 6-min walking distance increased significantly in comparison to baseline (p<0.01). The mean NSPS was also significantly increased after the inhalation of procaterol in comparison to baseline (p<0.01). The walking pattern was displayed on a graph of time versus NSPS, and the walking pace was shown by a graph of time versus cumulative steps. [Conclusion] The analysis of the COPD patients’ walking test performance and their walking pattern and pace in the 6MWT may help to evaluate the effects of drug treatment.
Publisher
The Japanese Society of Internal Medicine
Content Type
Journal Article
Link
ISSN
09182918
EISSN
13497235
Journal Title
INTERNAL MEDICINE
Current Journal Title
INTERNAL MEDICINE
Volume
56
Issue
15
Start Page
1949
End Page
1955
Published Date
2017
Publisher-DOI
Text Version
Publisher
Rights
© 2017 by The Japanese Society of Internal Medicine. The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Citation
Burioka Naoto, Nakamoto Sachiko, Amisaki Takashi, et al. A Modified Method for Examining the Walking Pattern and Pace of COPD Patients in a 6-min Walk Test Before and After the Inhalation of Procaterol. INTERNAL MEDICINE. 2017. 56(15). 1949-1955. doi:10.2169/internalmedicine.56.7961
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English
Web of Science Key ut
WOS:000407086600003