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Authors
Onda, Kanna Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine
Fukuhara, Takahiro Division of Otolaryngology, Head and Neck Surgery, Department of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine Researchers DB KAKEN
Matsuda, Eriko Division of Otolaryngology, Head and Neck Surgery, Department of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine
Donishi, Ryohei Division of Otolaryngology, Head and Neck Surgery, Department of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine
Hirooka, Yasuaki Department of Surgery, Tottori Prefectural Central Hospital Researchers DB KAKEN
Takeuchi, Hiromi Division of Otolaryngology, Head and Neck Surgery, Department of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine Researchers DB KAKEN
Kato, Masahiko Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine Researchers DB KAKEN
Keywords
alivary gland
sialadenitis
Sj?gren’s syndrome
thyroid
ultrasonography
Abstract
Background: Ultrasonography is superior to other imaging modalities for detecting salivary gland diseases. However, there have been no reports of the results of salivary gland screening with ultrasonography. In this study, the salivary glands were also observed during thyroid ultrasonography to determine the degree of salivary gland abnormalities detected by ultrasonography.

Methods: This study was conducted retrospectively using medical records. It assessed the association between the following abnormal findings detected during thyroid ultrasonography and their final diagnoses: atrophy/swelling, unclear demarcation from surrounding tissues, decreased salivary gland parenchyma echo level, heterogeneity of parenchyma, hypervascularity of salivary gland parenchyma, dilatation of the ducts, and a mass within the gland.

Results: Of the 908 patients who underwent thyroid ultrasonography, salivary gland abnormalities were detected in 36 (4.0%) patients. Of the 36 patients with abnormal ultrasonographic findings, 22 underwent further examination. Of the 22 patients, 16 received definitive diagnoses of salivary gland diseases.

Salivary gland disorders were considered to be absent in patients with only heterogeneity of the salivary glands observed on ultrasonography. Salivary gland disorders in all patients with further abnormal ultrasonographic findings such as atrophy/swelling, unclear boundary, or hypervascularity in addition to internal heterogeneity were confirmed by further blood examinations and imaging studies. We were able to detect autoimmune sialadenitis such as Sj?gren’s syndrome and IgG4-related sialadenitis by ultrasonography in patients without obvious symptoms.

Conclusion: Salivary gland screening during thyroid ultrasonography revealed abnormal findings including Sj?gren’s syndrome and IgG4-related sialadenitis in about 4% of the patients. Thus, ultrasonography may also be useful for early detection of autoimmune diseases of salivary glands.
Publisher
Tottori University Medical Press
Content Type
Journal Article
Link
ISSN
0513-5710
EISSN
1346-8049
NCID
AA00892882
Journal Title
Yonago Acta Medica
Current Journal Title
Yonago Acta Medica
Volume
63
Issue
1
Start Page
42
End Page
46
Original Article
Published Date
2020-2-20
Publisher-DOI
Text Version
Publisher
Rights
注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.
Citation
Kanna Onda, Takahiro Fukuhara, Eriko Matsuda, Ryohei Donishi, Yasuaki Hirooka, Hiromi Takeuchi, Masahiko Kato, Impact of Screening for Salivary Gland by Ultrasonography, Yonago Acta Medica, 2020, Volume 63, Issue 1, Pages 42-46, Released February 20, 2020
Department
Faculty of Medicine/Graduate School of Medical Sciences/University Hospital
Language
English