ID 14057
フルテキストファイル
著者
Ikeda, Suguru Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University
杉原 誉明 Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University 研究者総覧 KAKEN
Kihara, Takuya Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University
Hoshino, Yoshiki Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University
Matsuki, Yukako Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University
永原 天和 Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University 研究者総覧
大山 賢治 Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University 研究者総覧
岡野 淳一 Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University 研究者総覧 KAKEN
桑本 聡史 Department of Pathology, Tottori University Hospital 研究者総覧 KAKEN
堀江 靖 Department of Pathology, Tottori University Hospital 研究者総覧 KAKEN
磯本 一 Division of Medicine and Clinical Science, Department of Gastroenterology and Nephrology, School of Medicine, Faculty of Medicine, Tottori University 研究者総覧 KAKEN
キーワード
autoimmune hepatitis
chronic active EBV infection
EBV-encoded small RNA1
Epstein–Barr virus
抄録
Chronic active Epstein–Barr virus (CAEBV) infection is a rare disease, mainly affecting children, typically characterized by persistent infectious mononucleosis (IM)-like symptoms. We describe an adult case of CAEBV without IM-like symptoms, which was indistinguishable from autoimmune hepatitis (AIH). A 60-year-old woman with liver damage was diagnosed with AIH (International Diagnostic Score: 16 points). She had been treated with prednisolone for three years; however, her transaminases had never normalized. She was admitted for another liver biopsy due to repeated high fevers and worsening of her liver damage over two months. Her EBV-DNA copy number was 2.9 × 104 copies/μg DNA, and EBV-encoded small RNA1-positive lymphocytic infiltration was observed in both the present and previously collected (three years ago) liver tissue samples. This case implies that hepatic involvement in a CAEBV without IM-like symptoms is difficult to distinguish from AIH and may be misdiagnosed. In some steroid resistant AIH cases, evaluating for CAEBV may be valuable.
出版者
Tottori University Medical Press
資料タイプ
学術雑誌論文
外部リンク
ISSN
05135710
EISSN
13468049
書誌ID
AA00892882
掲載誌名
Yonago Acta Medica
最新掲載誌名
Yonago Acta Medica
65
2
開始ページ
160
終了ページ
165
発行日
2022-05-23
出版者DOI
著者版フラグ
出版社版
著作権表記
(C) 2022 Tottori University Medical Press.
掲載情報
Yonago Acta Medica. 2022, 65(2), 160-165. doi10.33160/yam.2022.05.003
部局名
医学部・医学系研究科・医学部附属病院
言語
英語