フルテキストファイル
Thumnail 125-131.pdf 648 KB
著者
Burioka Naoto Third Department of Internal Medicine, Faculty of Medicine, Tottori University 研究者総覧 KAKEN
Suyama Hisashi Third Department of Internal Medicine, Faculty of Medicine, Tottori University 研究者総覧
Sugimoto Yuji Third Department of Internal Medicine, Faculty of Medicine, Tottori University
Chikumi Hiroki Third Department of Internal Medicine, Faculty of Medicine, Tottori University 研究者総覧 KAKEN
Yajima Hiroki Third Department of Internal Medicine, Faculty of Medicine, Tottori University
Tomita Katsuyuki Third Department of Internal Medicine, Faculty of Medicine, Tottori University
Hoshino Eiji Third Department of Internal Medicine, Faculty of Medicine, Tottori University
Matsumoto Yukio Third Department of Internal Medicine, Faculty of Medicine, Tottori University KAKEN
Sasaki Takao Third Department of Internal Medicine, Faculty of Medicine, Tottori University
Motoi Makoto Second Department of Pathology, Faculty of Medicine, Tottori University
キーワード
human T-cell lymphotropic virus type I
HTLV-I associated bronchiolo-alveolar disorder
HTLV-I associated bronchopneumopathy
interstitial pneumonia
pulmonary fibrosis
抄録
Two carriers of human T-cell lymphotropic virus type I (HTLV-I) with interstitial pneumonia are described. The first case, a 60-year-old man, was admitted with cough and dyspnea on exertion. Light microscopy of a lung specimen obtained by a transbronchial lung biopsy (TBLB ) showed thickening of the alveolar walls with infiltration of lymphocytes and fibrosis of the pulmonary parenchyma. Immunohistochemical analysis of the TBLB specimen showed positive staining in the lymphocytes for UCHL-1. This case was suspected as HTLV-I associated bronchiolo-alveolar disorder. The second case, a 74-year-old man, visited our hospital because of a persistent productive cough and dyspnea on exertion. Light microscopy of the TBLB showed a slight thickening of the alveolar walls and fibrosis of the pulmonary parenchyma with minimal infiltration of lymphocytes. Only 2.2% of the bronchoalveolar lavage fluid consisted of lymphocytes. The findings of the second case suggest that some factors other than T-lymphocytes may be related with the development of interstitial pneumonia in HTLV-I carriers. Interstitial pneumonia in HTLV-I carriers may be caused by as yet undiscovered mechanisms. A cohort study involving residents of an area where HTLV-I is endemic should be conducted to clarify the mechanism of pulmonary involvement in HTLV-I carriers.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
40
2
開始ページ
125
終了ページ
131
発行日
1997-07
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 1997, 40(2), 125-131
部局名
医学部・医学系研究科・医学部附属病院
言語
英語