フルテキストファイル
著者
Okuno, Keisuke Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine 研究者総覧
Yoneda, Naohiro Department of Pediatrics, Matsue City Hospital,
Nishimura, Rei Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine 研究者総覧
Sano, Hiroshi Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine
Ueyama, Jun-ichi Department of Pediatrics, Matsue City Hospital
Komatsu, Hiroaki Department of Obstetrics and Gynecology, Japanese Red Cross Yamaguchi Hospital
Harada, Tasuku Division of Reproductive-Perinatal Medicine and Gynecologic Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
Kuwamoto, Satoshi Division of Molecular Pathology, Department of Pathology, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
Horie, Yasushi Division of Molecular Pathology, Department of Pathology, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
Kanzaki, Susumu Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
キーワード
delayed puberty
interleukin-6
juvenile granulosa cell tumor
prolonged fever
抄録
Juvenile granulosa cell tumor (JGCT), classified as a sex cord-stromal tumor, is a rare neoplasm. This is an instructive case report of JGCT accompanied by augmented interleukin (IL)-6 secretion. A 13-year-old girl with prolonged fever and delayed puberty was diagnosed with JGCT of the left ovary based on an imaging study and pathological investigation. Although it was not clear whether IL-6 was secreted from the tumor cells, her serum level of IL-6 was very high. After tumorectomy, the patient’s symptoms immediately disappeared, her IL-6 level decreased, and she entered puberty. Therefore, augmented IL-6 secretion production induced by tumors should be considered a potential cause of prolonged fever and/or delayed puberty.
出版者
Tottori University Medical Press
資料タイプ
学術雑誌論文
外部リンク
ISSN
05135710
書誌ID
AA00892882
掲載誌名
Yonago Acta Medica
最新掲載誌名
Yonago Acta Medica
62
3
開始ページ
263
終了ページ
267
Patient Report
発行日
2019-09-13
出版者DOI
著者版フラグ
出版社版
著作権表記
注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.
掲載情報
Okuno K, Yoneda N, Nishimura R, Sano H, Ueyama J-i, Komatsu H, et al. Juvenile Granulosa Cell Tumor with Elevated Peripheral Interleukin-6 Level Shows Prolonged Fever and Delayed Puberty. Yonago Acta Medica. 2019;62:263-267.
部局名
医学部・医学系研究科・医学部附属病院
言語
英語