フルテキストファイル
著者
Izawa, Hironori Graduate School of Engineering, Tottori University 研究者総覧 KAKEN
Nishio, Shoji Graduate School of Engineering, Tottori University
Maeda, Hiroyuki Graduate School of Engineering, Tottori University
Morita, Kohei Graduate School of Engineering, Tottori University
Ifuku, Shinsuke Graduate School of Engineering, Tottori University 研究者総覧 KAKEN
Morimoto, Minoru Graduate School of Engineering, Tottori University 研究者総覧 KAKEN
Saimoto, Hiroyuki Graduate School of Engineering, Tottori University 研究者総覧 KAKEN
Kadokawa, Jun-ichi Graduate School of Science and Engineering, Kagoshima University
キーワード
Xanthan gum
Hydroxyapatite
Alternate soaking process
Inorganic–organic composite hydrogel
Mineralization
抄録
We previously reported a xanthan gum (Xan) hydrogel showing excellent mechanical properties. Mineralization of hydroxyapatite (Hap) upon the Xan hydrogel would provide a unique biomaterial applicable for bone tissue engineering. Here, we show the mineralization of Hap upon the Xan hydrogel by means of an alternate soaking process. Hap was gradually grown upon the Xan-matrix surface with increasing number of soaking cycles due to the ionic interactions between calcium cations and carboxyl groups. Interestingly, the mineralization induced a microstructure change in the gel-matrix from a layered structure to a porous structure. The mechanical properties of the resulting Hap–Xan composite hydrogels were further investigated by a tensile test, where the Hap–Xan composite hydrogel with an appropriate amount of Hap (Xan/Hap = 2.7) was capable of approximately 370% elongation.
出版者
Elsevier Ltd.
資料タイプ
学術雑誌論文
外部リンク
ISSN
01448617
書誌ID
AA11522761
掲載誌名
Carbohydrate Polymers
102
開始ページ
846
終了ページ
851
発行日
2014-02-15
出版者DOI
著者版フラグ
著者版
著作権表記
Copyright © 2014 Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
掲載情報
This research was published by Elsevier Ltd.: IZAWA, Hironori, et al. Mineralization of hydroxyapatite upon a unique xanthan gum hydrogel by an alternate soaking process. Carbohydrate polymers, 2014, 102: 846-851. https://doi.org/10.1016/j.carbpol.2013.10.080
部局名
工学部・工学研究科
言語
英語