フルテキストファイル
著者
Wakumoto, Keiko Division of Dermatology, Matsue Red Cross Hospital
Yoshida, Yuichi Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
Yamamoto, Osamu Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine
キーワード
basal cell carcinoma
inherited ichthyosis
X-linked recessive ichthyosis
抄録
We report a case of X-linked recessive ichthyosis with basal cell carcinoma. An 86-year-old man was referred to our department for evaluation of a 1-year history of an ulcer on his left leg. He had suffered from dry skin with scales on his entire body since childhood. Histopathological examination of the lower leg revealed intradermal proliferation of a solid nest of basaloid cells showing unclear palisading in the periphery. Marked hyperkeratosis and hypergranulosis were also seen in the adjacent dermis. Loss of the steroid sulfatase gene was found on chromosome X. Based on these finding, we made a diagnosis of X-linked recessive ichthyosis with basal cell carcinoma. To our knowledge, there has been no report of X-linked recessive ichthyosis with cutaneous malignancy. We discuss the risk of skin cancer in relation to ichthyosis.
出版者
Tottori University Medical Press
資料タイプ
学術雑誌論文
外部リンク
ISSN
05135710
書誌ID
AA00892882
掲載誌名
Yonago Acta Medica
最新掲載誌名
Yonago Acta Medica
63
1
開始ページ
92
終了ページ
94
Patient Report
発行日
2020-02-20
出版者DOI
著者版フラグ
出版社版
著作権表記
注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.
掲載情報
Keiko Wakumoto, Yuichi Yoshida, Osamu Yamamoto, Is X-linked Recessive Ichthyosis a High Risk for Basal Cell Carcinoma?, Yonago Acta Medica, 2020, Volume 63, Issue 1, Pages 92-94, Released February 20, 2020
部局名
医学部・医学系研究科・医学部附属病院
言語
英語