フルテキストファイル
著者
Horii Toshinobu Division of Bacteriology, Department of Microbiology and Immunology, School of Medicine, Tottori University Faculty of Medicine and Infection Control Division, Tottori University Hospital
キーワード
antimicrobial resistance
antimicrobial therapy
infection control
nosocomial infection
Pseudomonas aeruginosa
抄録
Pseudomonas aeruginosa remains one of the most difficult to treat and to control nosocomial infections. In vitro antimicrobial susceptibility data are required for successful therapy because acquired resistance to such antimicrobials as β-lactams, fluoroquinolones and aminoglycosides is so prevalent in P. aeruginosa. Strategies for controlling P. aeruginosa infections include early detection of P. aeruginosa as the causative pathogen, determination of its antimicrobial susceptibilities, initiation of effective and adequate therapy and strict infection control practice such as hand hygiene and equipment procedures. Once antimicrobial therapy has been initiated against a P. aeruginosa infection, its susceptibility to antimicrobials, especially to carbapenems and fluoroquinolones, should be monitored during antimicrobial therapy to detect clonal shifts in resistance and microbial substitutions as early as possible. Continued surveillance of nosocomial infections and monitoring of antimicrobial resistance by the infection control staff plays major roles in preventing nosocomial infections and the spread of antimicrobial resistance. Additional strategies for controlling antimicrobial resistance in P. aeruginosa include the development of new methods for rapid detection of antimicrobial resistance and new agents and vaccines against P. aeruginosa infections in the laboratories and pharmaceuticals, while preserving the efficacy of currently available antimicrobials for as long as possible in the hospital settings.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN・ISBN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
50
1
開始ページ
1
終了ページ
8
発行日
2007-03
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 2007, 50(1), 1-8
部局名
医学部・医学系研究科・医学部附属病院
言語
英語