フルテキストファイル
著者
Ohnishi Akemi Division of Molecular Pathology, Department of Microbiology and Pathology, School of Medicine, Tottori University Faculty of Medicine
Kitamura Yukisato Division of Molecular Pathology, Department of Microbiology and Pathology, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
Kato Masako Division of Molecular Pathology, Department of Microbiology and Pathology, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
Kawamura Yoshitomo Kawamura Clinic
Hayashi Kazuhiko Division of Molecular Pathology, Department of Microbiology and Pathology, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
キーワード
appendiceal tumor
pigmented neurofibroma
抄録
Pigmented (melanotic) neurofibromas in the appendix are extremely rare. To our knowledge, this is the first case of appendiceal pigmented neurofibroma in a patient without neurofibromatosis 1, which was colonoscopically diagnosed. Histologically, the tumor cells were spindle shaped with indistinct cell borders. The tumor cells had cytoplasms with many gray-brown pigments. Immunohistochemical examinations showed that the tumor cells were strongly positive for S-100 protein, and were focally positive for Melan-A. They were also diffusely positive for Leu7 (CD57), or neuron-specific enolase (NSE). No positive expression of tumor cells was observed for -smooth muscle actin, desmin, CD34, c-kit, HMB45. No mitotic figures were observed. The Ki-67 labeling index was less than 1%. The tumor was thus diagnosed as primary pigmented neurofibroma in the appendix. In the present case, tumor cells showed no mitotic activity and a Ki-67 index of less than 1%, suggesting a benign tumor.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN・ISBN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
50
3
開始ページ
65
終了ページ
68
発行日
2007-09
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 2007, 50(3), 65-68
部局名
医学部・医学系研究科・医学部附属病院
言語
英語