フルテキストファイル
著者
Otani Shinji Division of Organ Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine 研究者総覧 KAKEN
Kusagaya Hiromitsu National Institute of Polar Research
キーワード
Antarctica
cytokine
high altitude; interleukin-6
mountain sickness
抄録
We evaluated the impact of the extreme environmental conditions at high altitudes in Antarctica on health from the viewpoint of cytokines. The subjects were 7 men who joined an inland research party participating in the 40th Japanese Antarctic Research Expedition. They underwent serial hematological examinations during the expedition for over 100 days at high altitudes (the highest point was 3810 m). The serum concentration of erythropoietin (EPO) increased promptly, indicating its usefulness for altitude adaptation. The serum concentration of interleukin-6 (IL-6) increased at high altitudes, and showed 2 peaks. Changes in IL-6 levels did not correlate with arterial oxygen tension, serum C-reactive protein or EPO levels. Some psychological stress and various factors may be related to IL-6 levels. Since the subject who suffered bone fractures had a very high concentration of IL-6 and his symptoms of mountain sickness were severer than the others, elevation of IL-6 may be related with mountain sickness. All subjects remained in relatively good health for 3 months. It is thought that the human body can protect itself against extreme surroundings in Antarctica.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
46
2
開始ページ
29
終了ページ
34
発行日
2003-06
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 2003, 46(2), 29-34
部局名
医学部・医学系研究科・医学部附属病院
言語
英語