フルテキストファイル
著者
Ikeda Tetsuhiro Department of Urology, Faculty of Medicine, Tottori University
Sofikitis Nikolaos Department of Urology, Faculty of Medicine, Tottori University
キーワード
epididymis
spermatogenesis
testicular function
unilateral vasectomy
抄録
We evaluated the effects of unilateral obstruction of the vas deferens on testicular endocrine and exocrine function in rats. The left vas deferens was ligated and divided in 1-week-old Wistar rats. Additional rats of the same age underwent a sham operation. Bilateral testicular weight and epididymal weight were compared between the vasectomized and sham-operated animals at 4, 8 and 12 weeks postoperation. Intratesticular versus intraabdominal temperature difference, epididymal caudal sperm content (ECSC), motility (ECSM) and in vitro fertilizing capacity (IVF) were compared between the vasectomized and sham-operated animals at 12 weeks postoperation. Serum testosterone response to human chorionic gonadotropin and bilateral testicular weight were significantly smaller in the vasectomized animals than in the sham-operated animals at 8 and 12 weeks postoperation. Bilateral ECSC, ECSM and IVF outcomes were significantly smaller in vasectomized rats than in sham-treated rats 12 weeks postoperatively. Bilateral intratesticular versus intraabdominal temperature differences were not significantly different between the vasectomized and control rats at 12 weeks postoperation. Unilateral obstruction of the vas deferens results in a bilateral defect in spermatogenesis and in the epididymal sperm maturation process.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
ISSN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
43
1
開始ページ
1
終了ページ
9
発行日
2000-03
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 2000, 43(1), 1-9
部局名
医学部・医学系研究科・医学部附属病院
言語
英語