フルテキストファイル
著者
Nakabayashi Motoki Division of Organ Pathology, Department of Microbiology and Pathology, Tottori University Faculty of Medicine KAKEN
Shomori Kohei Division of Organ Pathology, Department of Microbiology and Pathology, Tottori University Faculty of Medicine KAKEN
Kiya Shuichi Clinic of Otorhinolaryngology, Sanin-Rosai Hospital
Shiomi Tatsushi Division of Organ Pathology, Department of Microbiology and Pathology, Tottori University Faculty of Medicine
Nosaka Kanae Division of Organ Pathology, Department of Microbiology and Pathology, Tottori University Faculty of Medicine 研究者総覧
Ito Hisao Division of Organ Pathology, Department of Microbiology and Pathology, Tottori University Faculty of Medicine KAKEN
キーワード
basal cell adenoma
immunohistochemistry
parotid gland
抄録
Basal cell adenoma (BCA) is an uncommon benign salivary gland neoplasm that includes isomorphic basaloid cells. We report on a female patient with BCA that developed in the right parotid gland in her 50s. The present patient demonstrated a few tumor nests in the fibrous capsule, and her tumor was larger than usual. These facts made us suspect of malignancy. Histopathologically, the tumor was characterized by multiple duct-like structures and tubular-trabecular masses composed of small isomorphic cells with hyperchromatic, round nuclei and an eosinophilic cytoplasm. It was difficult to determine whether the ductal structures noted in the tumor capsule were invasive. By immunohistochemistry, tumor cells of the tubular nests were positive for cytokeratin 7 and that the outer cells of tubular nests were positive for alpha smooth muscle actin (SMA) and calponin. Tumor cells were immuno-negative for S-100 protein and glial fibrillary acidic protein. The Ki-67 labeling scores of the cells were extremely low (< 1%). We could achieve an accurate diagnosis of BCA by immunohistochemistry with MIB-1 and other markers.
出版者
Tottori University Faculty of Medicine
資料タイプ
学術雑誌論文
外部リンク
ISSN・ISBN
1346-8049
書誌ID
AA00892882
掲載誌名
Yonago Acta medica
最新掲載誌名
Yonago Acta medica
53
3
開始ページ
65
終了ページ
69
発行日
2010-09
著者版フラグ
出版社版
著作権表記
Yonago Acta medica 編集委員会
掲載情報
Yonago Acta medica. 2010, 53(3), 65-69
部局名
医学部・医学系研究科・医学部附属病院
言語
英語