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Laparoscopy-Assisted Pylorus-Preserving Gastrectomy for Treating Early Gastric Cancer 20335532 Saito, Hiroaki Saito, Hiroaki 40623947 Fukumoto, Yoji Fukumoto, Yoji 10457161 Osaki, Tomohiro Osaki, Tomohiro Yamada, Yoshinori Fukuda, Kenji Tatebe, Shigeru Tsujitani, Shunichi 20193188 Ikeguchi, Masahide Ikeguchi, Masahide Yamada, Yoshinori Fukuda, Kenji Tatebe, Shigeru Tsujitani, Shunichi Yonago Acta medica　編集委員会 early gastric cancer laparoscopy-assisted pylorus-preserving gastrectomy pylorus preservation early gastric cancer laparoscopy-assisted pylorus-preserving gastrectomy pylorus preservation Laparoscopy-assisted pylorus-preserving gastrectomy (LAPPG) with lymphadenectomy has been used for treating early gastric cancer located in the middle-third of the stomach. However, firm evidence supporting its safety and usefulness is scant. This study examined 24 and 10 gastric adenocarcinoma patients who had undergone conventional pylorus-preserving gastrectomy (CPPG) and LAPPG, respectively, at our institution. Operation time for LAPPG (362.8 ± 49.6 min) was significantly longer than that for CPPG (221.9 ± 50.0 min; P = 0.04). Estimated blood loss with LAPPG (127.5 ± 91.2 mL) was not significantly different from that with CPPG (167.9 ± 149.9 mL; P = 0.44). Total number of resected lymph nodes was 26.3 ± 9.5 and 21.3 ± 10.8 with LAPPG and CPPG, respectively, with no statistically significant difference. C-reactive protein in serum on postoperative day 1 was significantly lower in the LAPPG than in the CPPG group (5.3 ± 1.7 mg/dL versus 7.8 ± 3.6 mg/dL; P = 0.049). The requirement for analgesia after surgery was more frequent in the CPPG than in the LAPPG group (3.7 ± 2.0 versus 2.2 ± 1.7; P = 0.04). Time to first flatus was shorter in the LAPPG than in the CPPG group (1.9 ± 0.9 days versus 3.1 ± 0.9 days; P = 0.0006). Postoperative hospital stay was significantly shorter in the LAPPG than in the CPPG group (12.0 ± 4.0 days versus 23.0 ± 10.7days; P = 0.0036). With regard to postoperative complications, stasis was observed more frequently in the CPPG (33.3%) than in the LAPPG (10%) group. In conclusion, patients treated by LAPPG showed a comparable quality of surgical operation compared with those treated by CPPG. Tottori University Faculty of Medicine 2008-06 eng journal article VoR https://repository.lib.tottori-u.ac.jp/records/5038 Yonago Acta medica. 2008, 51(2), 25-30 AA00892882 13468049 Yonago Acta medica Yonago Acta medica 51 2 25 30 https://repository.lib.tottori-u.ac.jp/record/5038/files/yam51(2)_025-030.pdf application/pdf 94.2 kB 2009-02-06