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トロンビンは時間的に2相性の血管反応を示し、その機序はPAR-1受容体とPKCを介する内皮NO合成酵素の異なるリン酸化にある Thrombin induces a temporal biphasic vascular response through the differential phosphorylation of endothelial nitric oxide synthase via protease-activated receptor-1 and protein kinase C 岡村, 昌宏 オカムラ, アキヒロ Okamura, Akihiro オカムラ, アキヒロ open access (C) 2022 The Authors. Production and hosting by Elsevier B.V. on behalf of Japanese Pharmacological Society. This is an open access article under the CC BY license(http://creativecommons.org/licenses/by/4.0/). eng doctoral thesis VoR https://repository.lib.tottori-u.ac.jp/records/6024 Okamura A, Miake J, Tomomori T, Takami A, Sawano T, Kato M, Ogura K, Tsujimoto D, Kawatani S, Agung K, P, Notsu T, Hisatome I, Yamamoto K, Imamura T. Thrombin induces a temporal biphasic vascular response through the differential phosphorylation of endoth 甲第993号 博士(医学) 2022-03-31 15101 鳥取大学 https://repository.lib.tottori-u.ac.jp/record/6024/files/G11_15101A00993.pdf application/pdf 780.6 kB 2022-06-29 https://repository.lib.tottori-u.ac.jp/record/6024/files/G11_15101A00993R.pdf application/pdf 195.0 kB 2022-06-29 https://repository.lib.tottori-u.ac.jp/record/6024/files/G11_15101A00993S.pdf application/pdf 132.3 kB 2022-06-29