2026-03-12T07:00:29Z https://repository.lib.tottori-u.ac.jp/oai

oai:repository.lib.tottori-u.ac.jp:00004717 2023-09-28T23:51:49Z 1:9 2:12 23:34:988:989

Investigation of the Utility and Safety of Dynamic Computed Tomography with Vasodilators Watanabe, Jun Endo, Kanenori Tanaka, Yasutaka Goto, Keisuke Urushibara, Shoichi 10457161 Osaki, Tomohiro Tatebe, Shigeru 20283997 Nakamura, Seiichi 40243399 Hirooka, Yasuaki 20193188 Ikeguchi, Masahide Yonago Acta medica　編集委員会 abdomen computed tomography liver vasodilator agents abdomen computed tomography liver vasodilator agents Background: Dynamic computed tomography (CT) angiography is useful for evaluating of hepatic vascularity. Although vasodilators increase hepatic blood flow, the utility of dynamic CT with vasodilators is unclear. Here we investigated the utility and safety of dynamic CT with vasodilators. Methods: A prospective case-control radiographic evaluation using abdominal dynamic CT with and without vasodilator was performed at a single center between October 2015 and September 2016. We compared the CT values in Hounsfield units of the aorta; celiac artery; and common, right, and left hepatic arteries in the arterial phase and the main trunk; right and left branches of the portal vein; and right, middle, and left hepatic veins in the portal phase with and without vasodilators. The region of interest was set in each element of the liver vasculature. Four radiological technologists independently and visually compared the scores of the portal vein (P-score) and hepatic vein (V-score) on a 5-point scale with and without vasodilators. Results: The CT values of arteries and veins using vasodilators were significantly higher than those without vasodilators. With and without vasodilators, the P-scores were 3.1 ± 1.2 and 4.0 ± 1.1 (P < 0.05) and the V-scores were 3.3 ± 1.4 and 4.3 ± 1.0 (P < 0.05). Only one patient with vasodilator use had transient hypotension and recovered immediately without medication. Conclusion: Dynamic CT with vasodilators can provides better visualization of vascular structures. Tottori University Medical Press 2020-02-20 eng journal article VoR https://repository.lib.tottori-u.ac.jp/records/4717 10.33160/yam.2020.02.007 Jun Watanabe, Kanenori Endo, Yasutaka Tanaka, Keisuke Goto, Shoichi Urushibara, Tomohiro Osaki, Shigeru Tatebe, Seiichi Nakamura, Yasuaki Hirooka, Masahide Ikeguchi, Investigation of the Utility and Safety of Dynamic Computed Tomography with Vasodilators, https://www.jstage.jst.go.jp/article/yam/63/1/63_2020.02.007/_article/ https://www.jstage.jst.go.jp/article/yam/63/1/63_2020.02.007/_article/ http://www.lib.tottori-u.ac.jp/yam/yam/yam63-1/63-1contents.html http://www.lib.tottori-u.ac.jp/yam/yam/yam63-1/63-1contents.html AA00892882 05135710 Yonago Acta Medica Yonago Acta Medica 63 1 47 54 https://repository.lib.tottori-u.ac.jp/record/4717/files/yam63(1)_47.pdf application/pdf 1.4 MB 2023-03-15