{"created":"2024-08-27T00:34:24.067140+00:00","id":2001481,"links":{},"metadata":{"_buckets":{"deposit":"d5079f01-3dbf-4ce6-8e57-511207e4ddad"},"_deposit":{"created_by":10,"id":"2001481","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"2001481"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:02001481","sets":["1:9","2:12"]},"author_link":["2308"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2024-08","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{"bibliographic_title":"European Journal of Neuroscience","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The subventricular zone (SVZ) is one of the neurogenic regions of the adult mammalian brain. Neural stem cells (NSCs) in the SVZ have certain key features: they express glial fibrillary acidic protein (GFAP), proliferate slowly, have a radial glia?like (RG-L) morphology, and are in contact with the cerebrospinal fluid (CSF). NSCs have been isolated by FACS to analyse them, but their morphology has not been systematically examined. To address this knowledge gap, we sparsely labelled RG-L cells in the SVZ of neonatal mice by introducing via electroporation a plasmid expressing fluorescent protein under the control of the GFAP promoter. We then classified RG-L cells into three types (RG-L1, 2, and 3) based on their morphologies. RG-L1 cells had a basal process with some branches and numerous fine processes. RG-L2 cells had a basal process, but fewer branches and fine processes than RG-L1 cells. RG-L3 cells had one basal process that was almost free of branches and fine processes. Importantly, regardless of the cell type, about half of their somata resided on the basal side of the SVZ. Based on changes in their proportions during postnatal development and their expression of GFAP and cell proliferation markers at the adult stage, we speculated that NSCs change their morphologies during development/maturation and not all NSCs must always be in the apical SVZ or in contact with the CSF. Our results indicate that in addition to expression of markers for NSCs, the morphology is a critical feature to identify NSCs.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Federation of European Neuroscience Societies","subitem_publisher_language":"en"},{"subitem_publisher":"John Wiley & Sons Ltd","subitem_publisher_language":"en"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yoshida, R., & Mori, T. (2024). Morphological classification of radial glia–like cells in the postnatal mouse subventricular zone. European Journal of Neuroscience, 1–13. https://doi.org/10.1111/ejn.16503"}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://doi.org/10.1111/ejn.16503"}],"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/ejn.16503","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is the pre-peer reviewed version of the following article: [Yoshida, R., & Mori, T. (2024). Morphological classification of radial glia– like cells in the postnatal mouse subventricular zone. European Journal of Neuroscience, 1–13]. which has been published in final form at [https://doi.org/10.1111/ejn.16503]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0953816X","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"14609568","subitem_source_identifier_type":"EISSN"}]},"item_10001_text_33":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"embargoed access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_f1cf"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"15101","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"鳥取大学","affiliationNameLang":"ja"},{"affiliationName":"Tottori University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Ryota,Yoshida","creatorNameLang":"en"},{"creatorName":"ヨシダ,リョウタ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Ryota","familyNameLang":"en"},{"familyName":"ヨシダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yoshida","givenNameLang":"en"},{"givenName":"リョウタ","givenNameLang":"ja-Kana"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"15101","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"鳥取大学","affiliationNameLang":"ja"},{"affiliationName":"Tottori University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"森,徹自","creatorNameLang":"ja"},{"creatorName":"Tetsuji,Mori","creatorNameLang":"en"},{"creatorName":"モリ,テツジ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"森","familyNameLang":"ja"},{"familyName":"Tetsuji","familyNameLang":"en"},{"familyName":"モリ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"徹自","givenNameLang":"ja"},{"givenName":"Mori","givenNameLang":"en"},{"givenName":"テツジ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2308","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"100001237","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100001237ja.html"},{"nameIdentifier":"30285043","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30285043"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2025-08-31"}],"displaytype":"detail","fileDate":[{"fileDateType":"Issued","fileDateValue":"2024-08-10"}],"filename":"ejn_ejn.16503.pdf","format":"application/pdf","licensefree":"This is the pre-peer reviewed version of the following article: [Yoshida, R., & Mori, T. (2024). Morphological classification of radial glia– like cells in the postnatal mouse subventricular zone. European Journal of Neuroscience, 1–13]. which has been published in final form at [https://doi.org/10.1111/ejn.16503]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ejn_ejn.16503.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/2001481/files/ejn_ejn.16503.pdf"},"version_id":"85fe398d-8978-4b5f-9b21-14dce049f8ed"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"adult neural stem cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"adult neurogenesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"differentiation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"GFAP","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radial glia–like cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"subventricular zone","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Morphological classification of radial glia–like cells in the postnatal mouse subventricular zone","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Morphological classification of radial glia–like cells in the postnatal mouse subventricular zone","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-09-04"},"publish_date":"2024-09-04","publish_status":"0","recid":"2001481","relation_version_is_last":true,"title":["Morphological classification of radial glia–like cells in the postnatal mouse subventricular zone"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-09-04T05:05:33.754970+00:00"}