{"created":"2023-08-02T03:55:24.625907+00:00","id":4329,"links":{},"metadata":{"_buckets":{"deposit":"3c4d1562-6983-4b94-8604-85d327ac8503"},"_deposit":{"created_by":10,"id":"4329","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"4329"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00004329","sets":["1:9","2:14","23:40:806:807"]},"author_link":["37486","37487","3499","4213","765","37488","37489"],"item_3_alternative_title_31":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"フコイダン　ゼントウヨ　ニ　ヨリ　ユウドウ　サレル　キョケツシ　ノ　ケッカン　シンセイ　サヨウ　ニ　カンスル　ケンキュウ","subitem_alternative_title_language":"ja-Kana"}]},"item_3_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"24","bibliographicPageStart":"16","bibliographicVolumeNumber":"69","bibliographic_titles":[{"bibliographic_title":"米子医学雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"The Journal of the Yonago Medical Association","bibliographic_titleLang":"en"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【Background】Peripheral artery disease（ PAD） caused the poor prognosis of the patients. The life style intervention is necessary to protect patients from PAD. Fucoidan is the member of the polysaccharide originated from Mozuku sea weed, which is useful supplement for life style related disease. 【Purpose】We examined whether fucoidan could improve limb ischemic lesions in mice and rats. 【Method and Result】We created the ischemic limb model of mice and rats and evaluated their blood flow using the laser Doppler blood perfusion. We separated them into three groups, control group （without any treatment），post-treatment group （treated with fucoidan after ischemia for 4 weeks），and pre- and post-treatment group （treated with fucoidan before ischemia for 1 week and after ischemia for 4 weeks）．Fucoidan significantly improved the blood perfusion of ischemic limb in pre- and post-treatment group compared to those in control group. Neovascularization was remarkably increased in muscle of ischemic limb in pre- and post-treatment group compared to those in control group. Fucoidan did not improve either the blood perfusion or neovascularization in post-treatment group. 【Conclusion】Pretreatment with fucoidan through oral administration would be a promising supplement for protection from PAD.","subitem_description_type":"Other"}]},"item_3_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"米子医学会"}]},"item_3_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"野津智美, 櫻木哲詩, 陶山淑子 他. フコイダン前投与により誘導される虚血肢の血管新生作用に関する研究. 米子医学雑誌. 2018, 69(1-2), 16-24."}]}]},"item_3_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://mol.medicalonline.jp/library/journal/abstract?GoodsID=eb3yonai/2018/006901/003&name=0016-0024"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://mol.medicalonline.jp/library/journal/abstract?GoodsID=eb3yonai/2018/006901/003&name=0016-0024","subitem_relation_type_select":"URI"}}]},"item_3_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted."}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00247383","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00440558","subitem_source_identifier_type":"ISSN"}]},"item_3_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"鳥取大学大学院医学系研究科　機能再生医科学専攻"},{"subitem_text_value":"山陰労災病院　内科"},{"subitem_text_value":"鳥取大学医学部附属病院　形成外科"},{"subitem_text_value":"鳥取大学医学部附属病院　形成外科"},{"subitem_text_value":"鳥取大学大学院医学系研究科　機能再生医科学専攻"}]},"item_3_text_33":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Graduate School of Medical Science, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Department of Medicine, Sanin Rosai Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Graduate School of Medical Science, Tottori University"}]},"item_3_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"野津, 智美"},{"creatorName":"ノツ, トモミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"櫻木, 哲詩"},{"creatorName":"サクラギ, テツシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"陶山, 淑子"},{"creatorName":"スヤマ, ヨシコ","creatorNameLang":"ja-Kana"},{"creatorName":"Suyama, Yoshiko","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"八木, 俊路朗"},{"creatorName":"ヤギ, シュンジロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Yagi, Shunjiro","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"久留, 一郎"},{"creatorName":"ヒサトメ, イチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Hisatome, Ichiro","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Notsu, Tomomi","creatorNameLang":"en"},{"creatorName":"ノツ, トモミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakuragi, Tetsushi","creatorNameLang":"en"},{"creatorName":"サクラギ, テツシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-28"}],"displaytype":"detail","filename":"jyma69(1-2)_16.pdf","filesize":[{"value":"973.5 kB"}],"format":"application/pdf","licensefree":"注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jyma69(1-2)_16.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/4329/files/jyma69(1-2)_16.pdf"},"version_id":"533c1a0d-a84d-46a9-ab7f-12be485768ff"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"fucoidan","subitem_subject_scheme":"Other"},{"subitem_subject":"PAD","subitem_subject_scheme":"Other"},{"subitem_subject":"neovascularization","subitem_subject_scheme":"Other"},{"subitem_subject":"fucoidan","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"PAD","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"neovascularization","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper"}]},"item_title":"フコイダン前投与により誘導される虚血肢の血管新生作用に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"フコイダン前投与により誘導される虚血肢の血管新生作用に関する研究","subitem_title_language":"ja"},{"subitem_title":"Study on the neovascularization of limb ischemia induced by pretreatment with fucoidan","subitem_title_language":"en"}]},"item_type_id":"3","owner":"10","path":["9","14","807"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-06-22"},"publish_date":"2020-06-22","publish_status":"0","recid":"4329","relation_version_is_last":true,"title":["フコイダン前投与により誘導される虚血肢の血管新生作用に関する研究"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-09-27T01:20:06.852310+00:00"}