@article{oai:repository.lib.tottori-u.ac.jp:00004690, author = {中村, 陽祐 and Nakamura, Yosuke and 藤原, 和典 and Fujiwara, Kazunori and 黒崎, 雅道 and Kurosaki, Masamichi and 八島, 一夫 and Yashima, Kazuo and 竹内, 裕美 and Takeuchi, Hiromi and Nakamori, Motoki}, issue = {2}, journal = {Yonago Acta Medica, Yonago Acta Medica}, month = {May}, note = {We report the case of a 65-year-old male who presented with a 1-week history of right periorbital pain and progressive visual loss. He had a history of ulcerative colitis and was taking oral corticosteroids and mesalazine. Neurological and radiological examination demonstrated a rare case of invasive fungal rhinosinusitis that began with orbital apex syndrome. Initial endoscopic sinus surgery was performed and fungal culture identified Aspergillus fumigatus. Although antifungal treatment was started empirically before the operation, the patient had improved orbital pain but continued to have decreased right vision. Five months after the first surgical procedure, his condition deteriorated, including loss of consciousness, and a right temporal lobe abscess was found and surgically drained. Since then, the patient received antifungal treatment for 4 years without recurrence. Invasive fungal rhinosinusitis with orbital apex syndrome should be treated with long-term postoperative antifungal medication. It should be noted that even in immunosuppressive individuals such as ulcerative colitis, fungal rhinosinusitis with orbital apex syndrome may become severe.}, pages = {210--213}, title = {Invasive Fungal Rhinosinusitis with Orbital Apex Syndrome Leading to Brain Abscess in a Patient with Ulcerative Colitis}, volume = {64}, year = {2021}, yomi = {ナカムラ, ヨウスケ and フジワラ, カズノリ and クロサキ, マサミチ and ヤシマ, カズオ and タケウチ, ヒロミ} }