{"created":"2023-08-02T03:56:01.818610+00:00","id":5012,"links":{},"metadata":{"_buckets":{"deposit":"3a1371e0-9b40-4ad4-80b2-f0b79c01d424"},"_deposit":{"created_by":10,"id":"5012","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5012"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005012","sets":["1:9","2:12","23:34:1038:1040"]},"author_link":["4524","18370","18371","18372","18373","4246","4733","18374","18375","18376","18377"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"45","bibliographicPageStart":"37","bibliographicVolumeNumber":"53","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Probiotics (live microbial food supplements) have been shown to be effective in allergic diseases, but the potential of probiotics for treatment of adult atopic dermatitis is not clear. The effect of probiotic Bifidobacterium breve (B. breve) for atopic dermatitis was assessed in this study. A total of 24 patients were given either B. breve strain YY or a placebo for 8 weeks. Clinical severity was evaluated by using the severity scoring of atopic dermatitis and quality of life was assessed by Skindex-29-J. In addition, blood and fecal samples were taken before and after the study. The objective severity scoring for atopic dermatitis significantly improved in the probiotic group compared with the placebo group. In the quality of life assessment, the total score showed significant improvement in the probiotic group. The proportion of B. breve in intestinal microflora was increased in the probiotic group. However, no significant change in thymus and activation-regulated chemokine (TARC/CCL17), immunoglobulin E or the number of eosinophils was found. Our results suggest that B. breve may be beneficial for the treatment of atopic dermatitis. However, since the severity of disease symptoms in the placebo group at the beginning of the study was milder than those in the probiotic group because the number of patients in the present pilot study was relatively small, further study is needed to determine the clinical value of B. breve in adult patients with atopic dermatitis.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2010, 53(2), 37-45"}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.lib.tottori-u.ac.jp/yam/yam53-2/yam53_037-045.html"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.lib.tottori-u.ac.jp/yam/yam53-2/yam53_037-045.html","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Research and Development, Tokiwa Pharmaceutical"},{"subitem_text_value":"Research and Development, Tokiwa Pharmaceutical"},{"subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yoshida, Yuichi"},{"creatorName":"Yoshida, Yuichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4524","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70335975","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70335975"},{"nameIdentifier":"100000284","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000284_ja.html"}]},{"creatorNames":[{"creatorName":"Seki, Taizo"}],"nameIdentifiers":[{"nameIdentifier":"18370","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsunaka, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"18371","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Watanabe, Tessin"}],"nameIdentifiers":[{"nameIdentifier":"18372","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shindo, Masahisa"}],"nameIdentifiers":[{"nameIdentifier":"18373","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Nanako"},{"creatorName":"Yamada, Nanako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4246","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10304213","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=10304213"},{"nameIdentifier":"100000278","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000278_ja.html"}]},{"creatorNames":[{"creatorName":"Yamamoto, Osamu"},{"creatorName":"Yamamoto, Osamu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4733","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70174779","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70174779"},{"nameIdentifier":"100000279","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000279_ja.html"}]},{"creatorNames":[{"creatorName":"Seki, Taizo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18374","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsunaka, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18375","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Watanabe, Tessin","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18376","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shindo, Masahisa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18377","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2010-07-16"}],"displaytype":"detail","filename":"53_037-045.pdf","filesize":[{"value":"122.2 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"53_037-045.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5012/files/53_037-045.pdf"},"version_id":"8ce921c7-8fef-4aa2-9de7-d6fc4ce6d166"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"allergy","subitem_subject_scheme":"Other"},{"subitem_subject":"Bifidobacterium","subitem_subject_scheme":"Other"},{"subitem_subject":"intestinal","subitem_subject_scheme":"Other"},{"subitem_subject":"probiotics","subitem_subject_scheme":"Other"},{"subitem_subject":"quality of life","subitem_subject_scheme":"Other"},{"subitem_subject":"allergy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Bifidobacterium","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intestinal","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"probiotics","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"quality of life","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Clinical Effects of Probiotic Bifidobacterium breve Supplementation in Adult Patients with Atopic Dermatitis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clinical Effects of Probiotic Bifidobacterium breve Supplementation in Adult Patients with Atopic Dermatitis","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1040"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5012","relation_version_is_last":true,"title":["Clinical Effects of Probiotic Bifidobacterium breve Supplementation in Adult Patients with Atopic Dermatitis"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:49:11.461212+00:00"}