{"created":"2023-08-02T03:56:02.700827+00:00","id":5028,"links":{},"metadata":{"_buckets":{"deposit":"bfdda337-f1e0-4c27-bcba-60faa42dd4d0"},"_deposit":{"created_by":10,"id":"5028","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5028"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005028","sets":["1:9","2:12","23:34:1043:1045"]},"author_link":["1341","18450","1789","18451","2976","18452","18453","2989","18454","18455","18456","18457","18458","18459"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"90","bibliographicPageStart":"85","bibliographicVolumeNumber":"52","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Genomic imprinting is an epigenetic feature that plays a significant role in carcinogenesis. In this study, we examined the expression status of an imprinted gene, paternally expressed gene 1/mesoderm-specific transcript PEG1/MEST, in 38 cases of head and neck squamous cell carcinomas (HNSCCs) and in 17 oral squamous cancer cell lines. Loss of imprinting (LOI) of PEG1/MEST was found in 8 of 10 (80%) in tumor specimens, and 6 of 10 (60%) informative cases even in the extracted normal tissue specimens. As for the oral squamous cancer cell lines, LOI was detected in 5 of 8 (62.5%) informative cases in PEG1/MEST. Thus, these data showed that abnormal expression of PEG1/MEST was found at a high frequency in the tumor, the extracted normal tissue specimens and the oral squamous cancer cell lines. PEG1/MEST LOI in extracted normal tissue specimens may have a potential individual cancer risk for HNSCC.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2009, 52(2), 85-90"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Otolaryngology, Head and Neck Surgery, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Molecular Genetics and Biofunction, Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University"},{"subitem_text_value":"Division of Otolaryngology, Head and Neck Surgery, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Molecular Genetics and Biofunction, Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University"},{"subitem_text_value":"Division of Molecular Genetics and Biofunction, Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University"},{"subitem_text_value":"Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction, Graduate School, Tokyo Medical and Dental University"},{"subitem_text_value":"Biodosimetry Section, Department of Radiation Dosimetry, Research Center for Radiation Emergency Medicine, National Institute of Radiological Sciences"},{"subitem_text_value":"Division of Molecular Genetics and Biofunction, Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University"},{"subitem_text_value":"Division of Otolaryngology, Head and Neck Surgery, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kataoka, Hideyuki"},{"creatorName":"Kataoka, Hideyuki","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Nakano, Seiji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kunimoto, Yasuomi"},{"creatorName":"Kunimoto, Yasuomi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Sugie, Naoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Osaki, Mitsuhiko"},{"creatorName":"Osaki, Mitsuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Uzawa, Narikazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida, Mitsuaki A."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oshimura, Mitsuo"},{"creatorName":"Oshimura, Mitsuo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kitano, Hiroya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakano, Seiji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugie, Naoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uzawa, Narikazu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida, Mitsuaki A.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitano, Hiroya","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-07-30"}],"displaytype":"detail","filename":"52_085-090.pdf","filesize":[{"value":"152.9 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"52_085-090.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5028/files/52_085-090.pdf"},"version_id":"8f5d142b-00b4-41e2-87d9-b41d97172d1d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"head and neck squamous cell carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"loss of imprinting","subitem_subject_scheme":"Other"},{"subitem_subject":"PEG1/MEST","subitem_subject_scheme":"Other"},{"subitem_subject":"head and neck squamous cell carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"loss of imprinting","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"PEG1/MEST","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Allele-Specific Expression Analysis of PEG1/MEST in Head and Neck Squamous Cell Carcinomas","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Allele-Specific Expression Analysis of PEG1/MEST in Head and Neck Squamous Cell Carcinomas","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1045"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5028","relation_version_is_last":true,"title":["Allele-Specific Expression Analysis of PEG1/MEST in Head and Neck Squamous Cell Carcinomas"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:50:07.015184+00:00"}