{"created":"2023-08-02T03:56:04.260933+00:00","id":5052,"links":{},"metadata":{"_buckets":{"deposit":"02d4999f-d962-47a8-af02-47e6ce17f828"},"_deposit":{"created_by":10,"id":"5052","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5052"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005052","sets":["1:9","2:12","23:34:1053:1054"]},"author_link":["18622","18623","3905","18624","18625","1695","905","18626","18627","18628","18629"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"15","bibliographicPageStart":"9","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A small GTPase Rho protein and an effector ROCK have significant roles in cancer adhsion, metastasis, invasion, angiogenesis and cell mortality. We investigated the expressions of RhoA protein and ROCK-1 protein in 100 patients with macroscopically T3/T4 gastric cancer immunohistochemically. The expression of RhoA was detected in gastric cancer specimens from 39 patients and that of ROCK-1 in specimens from 30 patients. The clinicopathological characteristics of 21 tumors with co-expression of RhoA and ROCK-1 proteins (Rho/ROCK ON) were compared with those of the 79 remaining tumors (Rho/ROCK OFF). The percentage of lymph node metastasis positive cases in the Rho/ROCK ON group (81%) was higher than that in the Rho/ROCK OFF group (66%), but the difference was not significant (P = 0.183). However, the prognosis of the 21 patients with Rho/ROCK ON was significantly poorer than that of the 79 with Rho/ROCK OFF (P = 0.006). Our results indicate that the evaluation of the protein expression of RhoA and ROCK-1 is useful for predicting the prognosis in patients with T3/T4 gastric cancer.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2007, 50(1), 9-15"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Taniguchi, Kenjiro"}],"nameIdentifiers":[{"nameIdentifier":"18622","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujitani, Shunichi"}],"nameIdentifiers":[{"nameIdentifier":"18623","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tokuyasu, Naruo"},{"creatorName":"Tokuyasu, Naruo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3905","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"100000393","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000393_ja.html"}]},{"creatorNames":[{"creatorName":"Naka, Takuji"}],"nameIdentifiers":[{"nameIdentifier":"18624","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatebe, Shigeru"}],"nameIdentifiers":[{"nameIdentifier":"18625","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kondo, Akira"},{"creatorName":"Kondo, Akira","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1695","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90304211","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90304211"}]},{"creatorNames":[{"creatorName":"Ikeguchi, Masahide"},{"creatorName":"Ikeguchi, Masahide","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"905","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20193188","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=20193188"}]},{"creatorNames":[{"creatorName":"Taniguchi, Kenjiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18626","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujitani, Shunichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18627","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naka, Takuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18628","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatebe, Shigeru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18629","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-09"}],"displaytype":"detail","filename":"50_009-015.pdf","filesize":[{"value":"212.2 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"50_009-015.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5052/files/50_009-015.pdf"},"version_id":"d488534e-ded9-480f-b05b-b6369237a182"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gastric carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"prognosis","subitem_subject_scheme":"Other"},{"subitem_subject":"RhoA","subitem_subject_scheme":"Other"},{"subitem_subject":"ROCK-1","subitem_subject_scheme":"Other"},{"subitem_subject":"gastric carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"prognosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"RhoA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ROCK-1","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Rho-ROCK Expression Predicts the Prognosis in Patients with T3/T4 Gastric Cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Rho-ROCK Expression Predicts the Prognosis in Patients with T3/T4 Gastric Cancer","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1054"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5052","relation_version_is_last":true,"title":["Rho-ROCK Expression Predicts the Prognosis in Patients with T3/T4 Gastric Cancer"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:51:26.484632+00:00"}