{"created":"2023-08-02T03:56:04.455927+00:00","id":5055,"links":{},"metadata":{"_buckets":{"deposit":"8a887aab-c2f5-451b-a212-057f02897bd8"},"_deposit":{"created_by":10,"id":"5055","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5055"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005055","sets":["1:9","2:12","23:34:1053:1055"]},"author_link":["18640","18641","18642","18643","18644","18645","18646","18647","18648","18649","18650","18651"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"40","bibliographicPageStart":"33","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The effects of Bacteroides sp. strain T-40 isolated from human feces on the biotransformation of bile acids were examined in an anaerobic culture system. Bacteroides sp. T-40 oxidized cholic acid (CA) and chenodeoxycholic acid (CDCA) to 3α,12α-dihydroxy-7-oxo-5β-cholanoic acid and 3α-hydroxy-7-oxo-5β-cholanoic acid, and reduced these oxo-bile acids to CA and CDCA, respectively. However, the reduction activities were lower than the oxidation activities. Hyocholic acid was dehydrogenated, but to a lesser extent than CA or CDCA. On the other hand, α-muricholic acid, which has a hydroxyl group at the position of 7α, was not dehydrogenated. Glycocholic acid was converted to free 3α,12α-dihydroxy-7-oxo-5β-cholanoic acid but any glycine conjugated 7-oxo product was not detected. These data indicate that Bacteroides sp. T-40 possesses bile acid hydrolase and 7α-hydroxysteroid dehydrogenase, by which conjugated bile acids are initially deconjugated, and then undergo oxidization of the 7α-hydroxy group.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2007, 50(2), 33-40"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Medical Biochemistry, Department of Pathophysiological and Therapeutic Science, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Medical Biochemistry, Department of Pathophysiological and Therapeutic Science, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Functional Radiation Science, Research Center for BioScience and Technology, Tottori University"},{"subitem_text_value":"Division of Medical Biochemistry, Department of Pathophysiological and Therapeutic Science, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Laboratory of Veterinary Public Health, Graduate School of Agricultural and Life Sciences, The University of Tokyo"},{"subitem_text_value":"Division of Medical Biochemistry, Department of Pathophysiological and Therapeutic Science, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ogura, Yoshio"}],"nameIdentifiers":[{"nameIdentifier":"18640","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takei, Tsuyoshi"}],"nameIdentifiers":[{"nameIdentifier":"18641","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Takao"}],"nameIdentifiers":[{"nameIdentifier":"18642","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaga, Nobuo"}],"nameIdentifiers":[{"nameIdentifier":"18643","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Itoh, Kikuji"}],"nameIdentifiers":[{"nameIdentifier":"18644","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Kazuo"}],"nameIdentifiers":[{"nameIdentifier":"18645","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogura, Yoshio","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18646","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takei, Tsuyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18647","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Takao","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18648","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaga, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18649","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Itoh, Kikuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18650","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18651","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-09"}],"displaytype":"detail","filename":"50_033-040.pdf","filesize":[{"value":"479.2 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"50_033-040.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5055/files/50_033-040.pdf"},"version_id":"a30bae57-06e4-49c4-8e1c-3db5070eb24b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bacteroides","subitem_subject_scheme":"Other"},{"subitem_subject":"bile acid","subitem_subject_scheme":"Other"},{"subitem_subject":"biotransformation","subitem_subject_scheme":"Other"},{"subitem_subject":"dehydrogenase","subitem_subject_scheme":"Other"},{"subitem_subject":"hydrolase","subitem_subject_scheme":"Other"},{"subitem_subject":"Bacteroides","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bile acid","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"biotransformation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dehydrogenase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hydrolase","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Biotransformation of Bile Acids by Bacteroides sp. Strain T-40 Isolated from Human Microflora","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Biotransformation of Bile Acids by Bacteroides sp. Strain T-40 Isolated from Human Microflora","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1055"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5055","relation_version_is_last":true,"title":["Biotransformation of Bile Acids by Bacteroides sp. Strain T-40 Isolated from Human Microflora"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:51:37.904644+00:00"}