{"created":"2023-08-02T03:56:04.575777+00:00","id":5057,"links":{},"metadata":{"_buckets":{"deposit":"c1112099-dd37-4f45-a58d-d7baed9d4fcd"},"_deposit":{"created_by":10,"id":"5057","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5057"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005057","sets":["1:9","2:12","23:34:1053:1056"]},"author_link":["938"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"55","bibliographicPageStart":"45","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Cardiac preconditioning is the most potent and consistently reproducible method of protecting heart tissue against myocardial ischemia-reperfusion injury. This review discussed about the signaling and amplification cascades from either ischemic preconditioning stimulus or pharmacological preconditioning stimulus, the putative end-effectors and the mechanisms involved in cellular protection. The pharmacological preconditioning induced by volatile anesthetics and opioids is very similar to the ischemic preconditioning. It includes activation of G-protein-coupled receptors, multiple protein kinases and ATP-sensitive potassium channels (KATP channels). Volatile anesthetics prime the activation of the sarcolemmal and mitochondrial KATP channels, which are the putative end-effectors of preconditioning, by stimulation of adenosine receptors and subsequent activation of protein kinase C (PKC) and by increased formation of nitric oxide and free oxygen radicals. Similarly, opioids activate δ- and κ-opioid receptors leading to activation of PKC. The open state of the mitochondrial KATP channel and sarcolemmal KATP channel ultimately induces cytoprotection by decreasing Ca2+ overload in the cytosol and mitochondria.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2007, 50(3), 45-55"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Inagaki, Yoshimi"},{"creatorName":"Inagaki, Yoshimi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"938","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40184717","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40184717"},{"nameIdentifier":"100000092","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000092_ja.html"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-09"}],"displaytype":"detail","filename":"50_045-055.pdf","filesize":[{"value":"432.6 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"50_045-055.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5057/files/50_045-055.pdf"},"version_id":"369b0eab-6405-4e05-8b1d-9858202d39a4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ATP-sensitive potassium channel","subitem_subject_scheme":"Other"},{"subitem_subject":"ischemic preconditioning","subitem_subject_scheme":"Other"},{"subitem_subject":"pharmacological preconditioning","subitem_subject_scheme":"Other"},{"subitem_subject":"volatile anesthetic","subitem_subject_scheme":"Other"},{"subitem_subject":"opioid","subitem_subject_scheme":"Other"},{"subitem_subject":"ATP-sensitive potassium channel","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ischemic preconditioning","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pharmacological preconditioning","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"volatile anesthetic","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"opioid","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Cardiac Preconditioning by Anesthetic Agents: Roles of Volatile Anesthetics and Opioids in Cardioprotection","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Cardiac Preconditioning by Anesthetic Agents: Roles of Volatile Anesthetics and Opioids in Cardioprotection","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1056"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5057","relation_version_is_last":true,"title":["Cardiac Preconditioning by Anesthetic Agents: Roles of Volatile Anesthetics and Opioids in Cardioprotection"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:51:45.065908+00:00"}