@article{oai:repository.lib.tottori-u.ac.jp:00005068,
 author = {Kaetsu, Akihiko and Kaetsu, Akihiko and Kishimoto, Takuji and Kishimoto, Takuji and Osaki, Yoneatsu and Osaki, Yoneatsu and Okamoto, Mikizoh and Okamoto, Mikizoh and Kurozawa, Yoichi and Kurozawa, Yoichi},
 issue = {1},
 journal = {Yonago Acta medica, Yonago Acta medica},
 month = {Mar},
 note = {Angiotensinogen (AGT) is a component of the renin-angiotensin system, which plays a central role in blood pressure regulation. Although it is controversial, the association between AGT gene polymorphisms and hypertension, and coronary heart disease is suspected. In a case-control study on the metabolic syndrome, an association between AGT M235T polymorphism and serum total cholesterol (TC) level was demonstrated by Thomas et al. (2001). To reconfirm this relationship, a cross-sectional study among Japanese workers with 876 dyslipidemia and 1,158 non-dyslipidemia subjects was carried out. To evaluate the AGT M235T polymorphism, a PCR-mutant allele specific amplification (MASA) method was employed. No significant difference in the distribution of genetic variance was observed between the two groups. Although it was not significant, the T allele correlating to the lower TC of the present study occurred in a reversed manner to the previous report. In our results, no significant association between AGT M235T and TC was observed.},
 pages = {49--58},
 title = {Relationship between an Angiotensinogen Gene Polymorphism (M235T) and Serum Lipids: A Cross-Sectional Study among Japanese Workers},
 volume = {49},
 year = {2006}
}