{"created":"2023-08-02T03:56:05.340674+00:00","id":5069,"links":{},"metadata":{"_buckets":{"deposit":"d745339b-f683-442f-9001-f0d0e6feed27"},"_deposit":{"created_by":10,"id":"5069","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5069"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005069","sets":["1:9","2:12","23:34:1058:1059"]},"author_link":["1561","1203","2981","2880","18712","1839","18713","18714","18715"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"62","bibliographicPageStart":"59","bibliographicVolumeNumber":"49","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The relationship between cardiovascular disease and Glu298Asp polymorphism of nitric oxide synthase (eNOS) gene in vascular endothelial cells is controversial due to conflicting results. To demonstrate the effects of Glu298Asp polymorphism of the eNOS gene on eNOS gene expression by excluding the effects of various confounding factors, eNOS mRNA and protein expressions were measured using cultured human umbilical vein endothelial cells (HUVECs) according to genotypes of Glu298Asp polymorphism of the eNOS gene. eNOS mRNA expression was measured by real-time PCR/reverse trasnscription-PCR. eNOS protein expression was measured by an immunoassay method. HUVECs with Glu298Asp tended to show higher eNOS mRNA and protein expressions than those with Glu298Glu, but the difference was not significant. These results suggest that the genotypic difference of Glu298Glu and Glu298Asp has no effect on eNOS mRNA and protein expressions.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2006, 49(1), 59-62"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Health Administration and Promotion, Department of Social Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Reproductive-Perinatal Medicine and Gynecologic Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kishimoto, Takuji"},{"creatorName":"Kishimoto, Takuji","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kaetsu, Akihiko"},{"creatorName":"Kaetsu, Akihiko","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Osaki, Yoneatsu"},{"creatorName":"Osaki, Yoneatsu","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Okamoto, Mikizoh"},{"creatorName":"Okamoto, Mikizoh","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Nagai, Mariya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kurosawa, Yoichi"},{"creatorName":"Kurosawa, Yoichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Yoshida, Soichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagai, Mariya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida, Soichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-09"}],"displaytype":"detail","filename":"49_059-062.pdf","filesize":[{"value":"124.0 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"49_059-062.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5069/files/49_059-062.pdf"},"version_id":"3021970e-2af5-4966-a801-d800dd47b114"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gene expression","subitem_subject_scheme":"Other"},{"subitem_subject":"nitric oxide synthase","subitem_subject_scheme":"Other"},{"subitem_subject":"polymorphism","subitem_subject_scheme":"Other"},{"subitem_subject":"vascular endothelial cell","subitem_subject_scheme":"Other"},{"subitem_subject":"gene expression","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"nitric oxide synthase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"polymorphism","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"vascular endothelial cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Effects of Glu298Asp Polymorphism of Endothelial Nitric Oxide Synthase (eNOS) Gene on eNOS mRNA and Protein Expressions in Cultured Human Vascular Endothelial Cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Glu298Asp Polymorphism of Endothelial Nitric Oxide Synthase (eNOS) Gene on eNOS mRNA and Protein Expressions in Cultured Human Vascular Endothelial Cells","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1059"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5069","relation_version_is_last":true,"title":["Effects of Glu298Asp Polymorphism of Endothelial Nitric Oxide Synthase (eNOS) Gene on eNOS mRNA and Protein Expressions in Cultured Human Vascular Endothelial Cells"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:52:25.172128+00:00"}