{"created":"2023-08-02T03:56:05.933838+00:00","id":5080,"links":{},"metadata":{"_buckets":{"deposit":"ec349657-1a56-4f15-8fe7-5c014cab94d4"},"_deposit":{"created_by":10,"id":"5080","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5080"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005080","sets":["1:9","2:12","23:34:1063:1065"]},"author_link":["660"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"56","bibliographicPageStart":"41","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Epstein-Barr virus (EBV) is one of human herpesviruses and a member of the gamma herpesvirus family (lymphocryptovirus). Infectious mononucleosis, Burkitt's lymphoma and nasopharyngeal carcinoma are well-known EBV-associated diseases. The range of EBV-associated diseases has recently expanded to include Hodgkin's lymphoma, T-cell lymphoma, pyothorax-associated or methotrexate-associated B-cell lymphoma, primary effusion lymphoma and lymphoepithelioma-like carcinoma of the stomach, thymus and salivary gland, lymphoproliferative disorders (LPDs) or leiomyosarcomas from immunocompromized host, oral hairy leukoplakia and EBV-associated hemophagocytic syndrome. Animal models of human EBV-associated diseases are essential to elucidate the pathogenesis of EBV-infection and EBV-associated diseases. However, only several reports on the animal models of EBV infection have been reported. Here I review the summary of EBV-associated diseases in humans and those previous animal models using EBV or EBV-like herpesviruses and describe some details on our two newly developed rabbit models of LPD induced by simian EBV-like viruses and a mouse model with murine gammaherpesvirus. These animal models are useful and inexpensive alternative experimental model systems for studying the biology and pathogenesis of EBV, and prophylactic and therapeutic regimens.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2005, 48(2), 41-56"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Molecular Pathology, Department of Microbiology and Pathology, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayashi, Kazuhiko"},{"creatorName":"Hayashi, Kazuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"660","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30180962","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30180962"},{"nameIdentifier":"100000220","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000220_ja.html"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-09"}],"displaytype":"detail","filename":"48_041-056.pdf","filesize":[{"value":"409.4 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"48_041-056.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5080/files/48_041-056.pdf"},"version_id":"15d0a071-7fca-4655-8066-08f95be691c0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"animal model","subitem_subject_scheme":"Other"},{"subitem_subject":"EBV-associated disease","subitem_subject_scheme":"Other"},{"subitem_subject":"human","subitem_subject_scheme":"Other"},{"subitem_subject":"lymphocryptovirus","subitem_subject_scheme":"Other"},{"subitem_subject":"animal model","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"EBV-associated disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"human","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"lymphocryptovirus","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"EBV-Associated Diseases in Humans and their Animal in vivo Models: Part II","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"EBV-Associated Diseases in Humans and their Animal in vivo Models: Part II","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1065"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5080","relation_version_is_last":true,"title":["EBV-Associated Diseases in Humans and their Animal in vivo Models: Part II"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:53:04.026150+00:00"}