{"created":"2023-08-02T03:56:06.961956+00:00","id":5096,"links":{},"metadata":{"_buckets":{"deposit":"2aed7625-98b0-42ab-b025-15a2ab74ec22"},"_deposit":{"created_by":10,"id":"5096","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5096"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005096","sets":["1:9","2:12","23:34:1068:1072"]},"author_link":["702","18882","2183","18883"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"89","bibliographicPageStart":"81","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The effect of estradiol (E2) on the urinary bladder of old female rats was investigated by examining the histology and blood flow in the bladders. A total of 20 female Wistar rats aged 16 months were divided into 4 groups: Group I, 5 normal controls; Group II, 5 rats treated with E2 for 4 weeks; Group III, rats treated with E2 for 8 weeks; and Group IV, 5 rats receiving a placebo for 8 weeks. After the treatment, we removed the bladders, then weighed and stained them with hematoxylin and eosin. The muscle content was analyzed with the Elastica-van Gieson method, and the number of blood vessels with the Masson's trichrome method. Blood circulation in the bladders was also measured. The E2-replaced groups showed higher levels than the other groups in terms of blood flow in the bladder (20.6 ± 1.8 mL/min for Group II and 23.4 ± 1.5 mL/min for Group III, both P < 0.05 versus Groups I and IV), muscle content (2.33 ± 0.47 and 3.11 ± 0.48 for Groups II and III, respectively, both P < 0.05 versus Groups I and IV) and bladder weight (185.3 ± 6.2 mg and 193.2 ± 23.5 mg for Groups II and III; Group III showed P < 0.05 versus Groups I and IV). Differences in body weight and number of blood vessels among groups were not significant. We observed an increase in blood circulation, muscle content and weight of the bladder: E2-replacement therapy positively affected bladder functions.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2004, 47(4), 81-89"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"},{"subitem_text_value":"Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hikita, Katsuya"},{"creatorName":"Hikita, Katsuya","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Kobayashi, Naoto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyagawa, Ikuo"},{"creatorName":"Miyagawa, Ikuo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kobayashi, Naoto","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-09"}],"displaytype":"detail","filename":"47_081-089.pdf","filesize":[{"value":"579.0 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"47_081-089.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5096/files/47_081-089.pdf"},"version_id":"ea758613-aa64-4a00-b353-734ab8acfb05"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"bladder","subitem_subject_scheme":"Other"},{"subitem_subject":"blood flow","subitem_subject_scheme":"Other"},{"subitem_subject":"estrogen","subitem_subject_scheme":"Other"},{"subitem_subject":"rat","subitem_subject_scheme":"Other"},{"subitem_subject":"smooth muscle","subitem_subject_scheme":"Other"},{"subitem_subject":"bladder","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"blood flow","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"estrogen","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rat","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"smooth muscle","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Effect of Estrogen Replacement Therapy on Bladder Circulation in Old Female Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of Estrogen Replacement Therapy on Bladder Circulation in Old Female Rats","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1072"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5096","relation_version_is_last":true,"title":["Effect of Estrogen Replacement Therapy on Bladder Circulation in Old Female Rats"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:53:57.161064+00:00"}