{"created":"2023-08-02T03:56:09.462974+00:00","id":5139,"links":{},"metadata":{"_buckets":{"deposit":"d709901e-d94d-4c96-9c81-1c9ad37a2007"},"_deposit":{"created_by":10,"id":"5139","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5139"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005139","sets":["1:9","2:12","23:34:1083:1084"]},"author_link":["19060","19061","19062","19063","19064","19065","19066","19067","19068","19069"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"77","bibliographicPageStart":"69","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In order to clarify the effect of ileal bypass on cholesterol and bile acid metabolism, partial (20 cm) ileal bypass rats were fed a 2% cholesterol supplemented diet for a week after 4 weeks of the operation. The serum and liver cholesterol and phospholipid levels, biliary cholesterol, phospholipid and bile acid secretions, and fecal cholesterol, coprostanol and bile acid excretions were examined. The serum cholesterol level in ileal bypass rats was lower than in normal rats and no hypercholesterolemia was brought about in ileal bypass rats by feeding them the cholesterol diet. The liver cholesterol level increased by feeding the cholesterol diet even in ileal bypass rats but the increase was far less than that in normal rats (22% versus 57%). Biliary bile acid secretion decreased and fecal bile acid excretion increased markedly in ileal bypass rats. Deoxycholic acid increased remarkably in both bile and feces and resulted in an increase in the ratio of the sum of bile acids derived from cholic acid over the sum of bile acids derived from chenodeoxycholic acid (CA/CDCA ratio) in the feces. These results suggest that the absorption of bile acids is impaired, the pool size of bile acids decreases and the hepatic synthesis of bile acids, especially that of cholic acid, increases in ileal bypass rats. As a result, cholesterol feeding to ileal bypass rats produces neither hypercholesterolemia nor a further increase in bile acid synthesis.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2001, 44(1), 69-77"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Biochemistry, Tottori University Faculty of Medicine, The Cell Science Research Foundation"},{"subitem_text_value":"Shionogi & Co., Ltd."},{"subitem_text_value":"Department of Biochemistry, Tottori University Faculty of Medicine"},{"subitem_text_value":"Department of Biochemistry, Tottori University Faculty of Medicine"},{"subitem_text_value":"Department of Biochemistry, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Uchida, Kiyohisa"}],"nameIdentifiers":[{"nameIdentifier":"19060","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoh, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"19061","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogura, Yoshio"}],"nameIdentifiers":[{"nameIdentifier":"19062","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaga, Nobuo"}],"nameIdentifiers":[{"nameIdentifier":"19063","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Kazuo"}],"nameIdentifiers":[{"nameIdentifier":"19064","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Uchida, Kiyohisa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19065","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoh, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19066","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogura, Yoshio","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19067","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaga, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19068","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19069","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-08"}],"displaytype":"detail","filename":"44_069-077.pdf","filesize":[{"value":"176.6 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"44_069-077.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5139/files/44_069-077.pdf"},"version_id":"5f5c219c-4973-4bdb-84a6-ba2e25aede97"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"biliary lipids","subitem_subject_scheme":"Other"},{"subitem_subject":"fecal bile acids","subitem_subject_scheme":"Other"},{"subitem_subject":"fecal sterols","subitem_subject_scheme":"Other"},{"subitem_subject":"ileal bypass rat","subitem_subject_scheme":"Other"},{"subitem_subject":"serum and liver lipids","subitem_subject_scheme":"Other"},{"subitem_subject":"biliary lipids","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fecal bile acids","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fecal sterols","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ileal bypass rat","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"serum and liver lipids","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effect of Partial Ileal Bypass on Cholesterol and Bile Acid Metabolism in Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of Partial Ileal Bypass on Cholesterol and Bile Acid Metabolism in Rats","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1084"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5139","relation_version_is_last":true,"title":["Effect of Partial Ileal Bypass on Cholesterol and Bile Acid Metabolism in Rats"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:56:20.952168+00:00"}