{"created":"2023-08-02T03:56:09.658040+00:00","id":5142,"links":{},"metadata":{"_buckets":{"deposit":"ad833ffc-6a93-4582-875e-30234cbfd995"},"_deposit":{"created_by":10,"id":"5142","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5142"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005142","sets":["1:9","2:12","23:34:1083:1085"]},"author_link":["19080","19081","19082","19083","19084","19085","19086","19087","19088","19089"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"105","bibliographicPageStart":"91","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Gas chromatography is well recognized as a useful tool with several advantages for the analysis of bile acids as well as various compounds. In gas chromatographic analysis, bile acids in an analytical sample are subjected to a number of complicated procedures involving many steps such as extraction, fractionation, solvolysis, hydrolysis, derivatization and injection to the gas chromatograph. These procedures result in the loss of bile acids in the analytical sample. The addition of suitable internal standard compound(s) into the analytical sample prior to the extraction of bile acids is indispensable for an accurate determination of bile acids. There are two methods for the quantitative determination of bile acids in a biological sample by gas chromatography: one is the determination of total bile acid amounts in the sample. The other is the determination of bile acid amounts in each fraction after group separation of bile acids in the biological sample using an ion exchange gel column. The addition of 7β,12α-dihydroxy-5β-cholanoic acid or 7β,12β-dihydroxy-5β-cholanoic acid as an internal standard compound is useful for the former method. On the other hand, the addition of 7β,12β-dihydroxy-5β-cholanoic acid, glyco-7α,12α-dihydroxy-5β-cholanoic acid, tauro-7α,12β-dihydroxy-5β-cholanoic acid and glyco-7β,12α-dihydroxy-5β-cholanoic acid 7-sulfate is a suitable combination as internal standard compounds for the latter method.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 2001, 44(2), 91-105"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Biochemistry, Tottori University Faculty of Medicine"},{"subitem_text_value":"Department of Biochemistry, Tottori University Faculty of Medicine"},{"subitem_text_value":"Department of Biochemistry, Tottori University Faculty of Medicine"},{"subitem_text_value":"Department of Pathological Biochemistry, Tottori University Faculty of Medicine"},{"subitem_text_value":"The Cell Science Research Foundation"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamaga, Nobuo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ogura, Yoshio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamada, Kazuo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohara, Hiromi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uchida, Kiyohisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaga, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ogura, Yoshio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamada, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohara, Hiromi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uchida, Kiyohisa","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-08"}],"displaytype":"detail","filename":"44_091-105.pdf","filesize":[{"value":"498.2 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"44_091-105.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5142/files/44_091-105.pdf"},"version_id":"0245fc99-bb31-4bc9-84d2-b626e3236b51"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"bile acids","subitem_subject_scheme":"Other"},{"subitem_subject":"biological sample","subitem_subject_scheme":"Other"},{"subitem_subject":"gas chromatographic analysis","subitem_subject_scheme":"Other"},{"subitem_subject":"internal standard compounds","subitem_subject_scheme":"Other"},{"subitem_subject":"quantitative determination","subitem_subject_scheme":"Other"},{"subitem_subject":"bile acids","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"biological sample","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gas chromatographic analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"internal standard compounds","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"quantitative determination","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Internal Standard Compounds for Quantitative Determination of Bile Acids by Gas Chromatography","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Internal Standard Compounds for Quantitative Determination of Bile Acids by Gas Chromatography","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1085"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5142","relation_version_is_last":true,"title":["Internal Standard Compounds for Quantitative Determination of Bile Acids by Gas Chromatography"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:56:31.834485+00:00"}