{"created":"2023-08-02T03:56:11.534260+00:00","id":5179,"links":{},"metadata":{"_buckets":{"deposit":"d2182805-f0e4-4161-85fc-69c6e55a804e"},"_deposit":{"created_by":10,"id":"5179","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5179"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005179","sets":["1:9","2:12","23:34:1091:1092"]},"author_link":["19250","19251","2857","19252","19253","19254","1321","3378","19255","19256","19257","19258","19259"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"130","bibliographicPageStart":"125","bibliographicVolumeNumber":"42","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report a 3-year-old girl with steroid resistant nephrotic syndrome (NS) who developed nephrotoxicity by low-dose cyclosporin (CsA) treatment. Initial prednisolone (PSL) treatment and subsequent additional cyclophosphamide treatment were not successful in leading her into remission. The first renal biopsy finding revealed neither a glomerular nor interstitial change. CsA therapy was initiated in addition to ongoing glucocorticoid therapy at 6 months from the time of onset. Proteinuria disappeared 3 weeks later and the patient went into complete remission. After experiencing the first relapse, the patient was gradually weaned from CsA, and treatment continued with 30 to 50 ng/mL of trough concentration. No elevations of the serum creatinine, serum urea, serum potassium, excretion of urinary β2-microglobulin, or urinary N-acetyl-β-D-glucosaminidase were demonstrated in the follow-up. A second renal biopsy specimen obtained 1 year later showed a tubulo-interstitial change, containing tubular atrophy and interstitial fibrosis, both of which are consistent with the morphological change associated with CsA nephrotoxicity. A follow-up biopsy should be done in order to evaluate the CsA nephrotoxicity, regardless of the treatment dosage.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 1999, 42(1), 125-130"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Pediatrics, Faculty of Medicine, Tottori University"},{"subitem_text_value":"Department of Pediatrics, Faculty of Medicine, Tottori University"},{"subitem_text_value":"Department of Pediatrics, Faculty of Medicine, Tottori University"},{"subitem_text_value":"Department of Pediatrics, Faculty of Medicine, Tottori University"},{"subitem_text_value":"Department of Pediatrics, Faculty of Medicine, Tottori University"},{"subitem_text_value":"Department of Pediatrics, Faculty of Medicine, Tottori University"},{"subitem_text_value":"Department of Nursing, Institute of Medical Care Technology, Tottori University"},{"subitem_text_value":"Department of Pediatrics, Faculty of Medicine, Tottori University"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Utsunomiya, Yasushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Konishi, Kyoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okada, Shin-ichi"},{"creatorName":"Okada, Shin-ichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Sasaki, Yoshihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayashi, Atsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakagawa, Takako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kasagi, Tsunakiyo"},{"creatorName":"Kasagi, Tsunakiyo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Shiraki, Kazuo"},{"creatorName":"Shiraki, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Utsunomiya, Yasushi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Konishi, Kyoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sasaki, Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayashi, Atsushi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakagawa, Takako","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-08"}],"displaytype":"detail","filename":"42_125-130.pdf","filesize":[{"value":"117.1 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"42_125-130.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5179/files/42_125-130.pdf"},"version_id":"8d9d799d-3c29-473b-89cf-0b42c1e4eeaa"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"cyclosporin","subitem_subject_scheme":"Other"},{"subitem_subject":"nephrotic syndrome","subitem_subject_scheme":"Other"},{"subitem_subject":"nephrotoxicity","subitem_subject_scheme":"Other"},{"subitem_subject":"cyclosporin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"nephrotic syndrome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"nephrotoxicity","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"A Case of Nephrotic Syndrome with Nephrotoxicity Induced by Low-Dose Cyclosporin Treatment","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Case of Nephrotic Syndrome with Nephrotoxicity Induced by Low-Dose Cyclosporin Treatment","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1092"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5179","relation_version_is_last":true,"title":["A Case of Nephrotic Syndrome with Nephrotoxicity Induced by Low-Dose Cyclosporin Treatment"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:58:31.915316+00:00"}