{"created":"2023-08-02T03:56:11.750868+00:00","id":5184,"links":{},"metadata":{"_buckets":{"deposit":"b376019f-f34c-4165-9082-11d9fce3d3c3"},"_deposit":{"created_by":10,"id":"5184","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"5184"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00005184","sets":["1:9","2:12","23:34:1091:1093"]},"author_link":["19280","19281"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"161","bibliographicPageStart":"153","bibliographicVolumeNumber":"42","bibliographic_titles":[{"bibliographic_title":"Yonago Acta medica"},{"bibliographic_title":"Yonago Acta medica","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In 1868, Langerhans discovered the dendritic cells now generally called Langerhans cells (LCs) in the human epidermis using the gold impregnation method. He pointed out that the terminals of the upward running processes of the cells end with button-like swellings under the cornified layer. In 1951, Ferreira-Marques classified the shapes of the terminals into 7 types, named the largest one Organum trompiforme and reckoned it to be a sense receptor. However, the swellings of the process terminals seem to have been entirely forgotten along with the negation of the nerve cell theory of LCs. The author of this study recovered some of the actual forgotten terminals, the button-shaped (knopff?rmig) swellings of the process terminals of the cells, beneath the cornified layer of a healthy volunteer epidermis using the methylene blue staining method. Furthermore, the ultrastructures of the swellings were captured for the first time using the Thin-Section-Reembedding and Ultrathin-Sectioning (TRUS) technique named by the author. Investigation of the swellings by electron microscopy showed that there were a number of Birbeck granules and vacuoles of various sizes together with elements of cytoskeletons in the cytoplasm. Possibly this shows that LCs play an essential role in the differentiation of the epidermis at the process terminals.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tottori University Faculty of Medicine"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Yonago Acta medica. 1999, 42(2), 153-161"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Yonago Acta medica　編集委員会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00892882","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468049","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"First Department of Physiology, Faculty of Medicine, Tottori University"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oota, Shigeo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oota, Shigeo","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2009-06-08"}],"displaytype":"detail","filename":"42_153-161.pdf","filesize":[{"value":"749.1 kB"}],"format":"application/pdf","licensefree":"Yonago Acta medica　編集委員会","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"42_153-161.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/5184/files/42_153-161.pdf"},"version_id":"cf85b683-7f20-43b9-b5da-64af877fa033"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"electron microscopy","subitem_subject_scheme":"Other"},{"subitem_subject":"epidermis","subitem_subject_scheme":"Other"},{"subitem_subject":"Langerhans cells","subitem_subject_scheme":"Other"},{"subitem_subject":"methylene blue","subitem_subject_scheme":"Other"},{"subitem_subject":"electron microscopy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"epidermis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Langerhans cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"methylene blue","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Some New Aspects of Langerhans Cells in the Human Epidermis: Light and Electron Microscopic Observations on the Swelling Sites Seen in the Process Terminals of the Dendritic Cells Described by Langerhans in 1868","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Some New Aspects of Langerhans Cells in the Human Epidermis: Light and Electron Microscopic Observations on the Swelling Sites Seen in the Process Terminals of the Dendritic Cells Described by Langerhans in 1868","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9","1093"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-06-22"},"publish_date":"2018-06-22","publish_status":"0","recid":"5184","relation_version_is_last":true,"title":["Some New Aspects of Langerhans Cells in the Human Epidermis: Light and Electron Microscopic Observations on the Swelling Sites Seen in the Process Terminals of the Dendritic Cells Described by Langerhans in 1868"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-10-03T23:58:45.033904+00:00"}